ENSDARG00000101755


Danio rerio

Features
Gene ID: ENSDARG00000101755
  
Biological name :prkar1ab
  
Synonyms : prkar1ab / protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b
  
Possible biological names infered from orthology : P10644 / PRKAR1A / protein kinase, cAMP dependent regulatory, type I, alpha / protein kinase cAMP-dependent type I regulatory subunit alpha / Q9DBC7
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 2870671
Gene end: 2895802
  
Corresponding Affymetrix probe sets: Dr.16922.1.A1_at (Zebrafish Array)   NM_001017732_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000138282
NCBI entrez gene - 550427     See in Manteia.
RefSeq - NM_001017732
RefSeq Peptide - NP_001017732
swissprot - F1QEC8
ZFIN ID - ZDB-GENE-050417-238
Ensembl - ENSDARG00000101755
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5ZM91ENSGALG00000004237Gallus gallus
 P10644ENSG00000108946Homo sapiens
 Q9DBC7ENSMUSG00000020612Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prkar1aa / protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) aENSDARG0000007612893
prkar1b / protein kinase, cAMP-dependent, regulatory, type I, beta / P12849* / P31321* / protein kinase cAMP-dependent type I regulatory subunit beta*ENSDARG0000010380084
prkar2aa / protein kinase, cAMP-dependent, regulatory, type II, alpha A / P13861* / PRKAR2A* / protein kinase, cAMP dependent regulatory, type II alpha* / protein kinase cAMP-dependent type...ENSDARG0000003318436
prkar2ab / protein kinase, cAMP-dependent, regulatory, type II, alpha, B / P13861* / PRKAR2A* / protein kinase cAMP-dependent type II regulatory subunit alpha*ENSDARG0000000947734
PRKAR2B / si:ch211-272n13.7 / P31324* / P31323* / protein kinase, cAMP dependent regulatory, type II beta* / protein kinase cAMP-dependent type II regulatory subunit beta*ENSDARG0000003644634


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR003117  cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain
 IPR012198  cAMP-dependent protein kinase regulatory subunit
 IPR014710  RmlC-like jelly roll fold
 IPR018488  Cyclic nucleotide-binding, conserved site
 IPR018490  Cyclic nucleotide-binding-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0045859 regulation of protein kinase activity IEA
 cellular_componentGO:0005952 cAMP-dependent protein kinase complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0008603 cAMP-dependent protein kinase regulator activity IEA
 molecular_functionGO:0030552 cAMP binding IEA


Pathways (from Reactome)
Pathway description
PKA activation
PKA activation in glucagon signalling
DARPP-32 events
Vasopressin regulates renal water homeostasis via Aquaporins
Hedgehog off state
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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