ENSDARG00000102893


Danio rerio

Features
Gene ID: ENSDARG00000102893
  
Biological name :atg7
  
Synonyms : atg7 / ATG7 autophagy related 7 homolog (S. cerevisiae)
  
Possible biological names infered from orthology : autophagy related 7 / O95352 / Q9D906 / Ubiquitin-like modifier-activating enzyme ATG7
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 816106
Gene end: 891674
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000134373
Ensembl peptide - ENSDARP00000142048
Ensembl peptide - ENSDARP00000142189
Ensembl peptide - ENSDARP00000142239
Ensembl peptide - ENSDARP00000142484
swissprot - A0A0G2KPR3
swissprot - A0A140LFM5
swissprot - A0A140LG12
swissprot - A0A140LG61
swissprot - A0A140LGV5
ZFIN ID - ZDB-GENE-030131-1633
Ensembl - ENSDARG00000102893
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATG7ENSGALG00000004932Gallus gallus
 ATG7ENSG00000197548Homo sapiens
 Atg7ENSMUSG00000030314Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000594  THIF-type NAD/FAD binding fold
 IPR006285  Ubiquitin-like modifier-activating enzyme Atg7
 IPR032197  Ubiquitin-like modifier-activating enzyme Atg7, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IMP
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0000423 mitophagy IMP
 biological_processGO:0006501 C-terminal protein lipidation IBA
 biological_processGO:0006914 autophagy IMP
 biological_processGO:0006995 cellular response to nitrogen starvation IBA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0034727 piecemeal microautophagy of the nucleus IBA
 biological_processGO:0044805 late nucleophagy IBA
 cellular_componentGO:0000407 phagophore assembly site IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0008641 ubiquitin-like modifier activating enzyme activity IEA
 molecular_functionGO:0019778 Atg12 activating enzyme activity IBA
 molecular_functionGO:0019779 Atg8 activating enzyme activity IBA


Pathways (from Reactome)
Pathway description
Macroautophagy
Neutrophil degranulation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle mislocalised , abnormal
cardiac ventricle increased distribution , abnormal
cardiac ventricle orientation atrium , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000114 heart heart increased amount , abnormal
heart mislocalised , abnormal
heart increased distribution , abnormal
heart structure , abnormal
heart physical object quality , abnormal
heart autophagosome decreased amount , abnormal
Show

 ZFA:0000360 heart tube heart tube linear , abnormal
Show

 ZFA:0000471 atrium atrium mislocalised , abnormal
atrium increased distribution , abnormal
Show

 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism bent , abnormal
whole organism decreased amount , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region cell death increased occurrence , abnormal
Show

 ZFA:0001315 atrioventricular canal atrioventricular canal mislocalised , abnormal
atrioventricular canal increased distribution , abnormal
Show

 ZFA:0005237 erythroblast erythroblast mitophagy decreased occurrence , abnormal
Show

 ZFA:0009000 cell cell autophagosome assembly decreased process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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