ENSDARG00000102896


Danio rerio

Features
Gene ID: ENSDARG00000102896
  
Biological name :jmjd6
  
Synonyms : jmjd6 / jumonji domain containing 6 / Q6PFM0
  
Possible biological names infered from orthology : arginine demethylase and lysine hydroxylase / Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 / Q6NYC1 / Q9ERI5
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 60575113
Gene end: 60589292
  
Corresponding Affymetrix probe sets: Dr.18842.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000139813
NCBI entrez gene - 266962     See in Manteia.
swissprot - Q6PFM0
ZFIN ID - ZDB-GENE-040426-17
Ensembl - ENSDARG00000102896
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 JMJD6ENSGALG00000001802Gallus gallus
 JMJD6ENSG00000070495Homo sapiens
 Jmjd6ENSMUSG00000056962Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
jmjd4 / Q08BY5 / jumonji domain containing 4 / Q8BFT6* / Q9H9V9* / JmjC domain-containing protein 4 *ENSDARG0000005899522


Protein motifs (from Interpro)
Interpro ID Name
 IPR003347  JmjC domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002040 sprouting angiogenesis ISS
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006909 phagocytosis IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0048024 regulation of mRNA splicing, via spliceosome ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070078 histone H3-R2 demethylation IEA
 biological_processGO:0070079 histone H4-R3 demethylation IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm ISS
 cellular_componentGO:0005730 nucleolus ISS
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003727 single-stranded RNA binding ISS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0033746 histone demethylase activity (H3-R2 specific) ISS
 molecular_functionGO:0033749 histone demethylase activity (H4-R3 specific) ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA
 molecular_functionGO:0070815 peptidyl-lysine 5-dioxygenase activity ISS


Pathways (from Reactome)
Pathway description
HDMs demethylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain spatial pattern , abnormal
brain decreased size , abnormal
Show

 ZFA:0000009 cardiac ventricle cardiac ventricle aplastic , abnormal
Show

 ZFA:0000029 hindbrain hindbrain decreased size , abnormal
Show

 ZFA:0000037 anatomical structure anatomical structure spatial pattern , abnormal
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 ZFA:0000114 heart heart structure, cavities , abnormal
heart tubular , abnormal
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 ZFA:0000128 midbrain midbrain decreased size , abnormal
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 ZFA:0000135 notochord notochord bent , abnormal
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 ZFA:0000155 somite somite morphology , abnormal
somite decreased thickness , abnormal
somite apoptotic process increased occurrence , abnormal
Show

 ZFA:0000360 heart tube heart tube absent , abnormal
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 ZFA:0000471 atrium atrium aplastic , abnormal
Show

 ZFA:0001094 whole organism whole organism spatial pattern , abnormal
whole organism apoptotic process increased occurrence , abnormal
Show

 ZFA:0001135 neural tube neural tube morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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