ENSDARG00000103046


Danio rerio

Features
Gene ID: ENSDARG00000103046
  
Biological name :rest
  
Synonyms : RE1-silencing transcription factor / rest
  
Possible biological names infered from orthology : Q13127 / Q8VIG1
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 52418247
Gene end: 52433292
  
Corresponding Affymetrix probe sets: Dr.21280.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000136293
NCBI entrez gene - 564772     See in Manteia.
RefSeq - NM_001353866
RefSeq Peptide - NP_001340795
swissprot - A0A0R4IKA2
ZFIN ID - ZDB-GENE-080415-1
Ensembl - ENSDARG00000103046
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000032982Gallus gallus
 RESTENSG00000084093Homo sapiens
 RestENSMUSG00000029249Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
znf407 / zinc finger protein 407ENSDARG0000008753611


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR027757  RE1-silencing transcription factor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0050768 negative regulation of neurogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain increased amount , abnormal
Show

 ZFA:0000029 hindbrain hindbrain increased amount , abnormal
hindbrain mislocalised , abnormal
hindbrain increased distribution , abnormal
Show

 ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
Show

 ZFA:0000069 rhombomere 6 rhombomere 6 has fewer parts of type facial nerve motor nucleus motor neuron, abnormal
rhombomere 6 facial nerve motor nucleus increased volume , abnormal
Show

 ZFA:0000206 facial nerve motor nucleus facial nerve motor nucleus motor neuron migration decreased occurrence , abnormal
facial nerve motor nucleus motor neuron displaced to rhombomere 5 , abnormal
facial nerve motor nucleus motor neuron displaced to rhombomere 4 , abnormal
facial nerve motor nucleus mislocalised anteriorly , abnormal
facial nerve motor nucleus has extra parts of type motor neuron neuron projection, abnormal
facial nerve motor nucleus neuron maturation premature , abnormal
facial nerve motor nucleus neuron projection increased length , abnormal
facial nerve motor nucleus motor neuron circular , abnormal
facial nerve motor nucleus neuron projection increased amount , abnormal
facial nerve motor nucleus motor neuron increased volume , abnormal
facial nerve motor nucleus motor neuron migration occurrence , ameliorated
facial nerve motor nucleus motor neuron displaced to rhombomere 5 , ameliorated
facial nerve motor nucleus motor neuron displaced to rhombomere 4 , ameliorated
facial nerve motor nucleus neuron projection amount , ameliorated
facial nerve motor nucleus neuron projection length , ameliorated
facial nerve motor nucleus motor neuron shape , ameliorated
facial nerve motor nucleus motor neuron volume , ameliorated
facial nerve motor nucleus motor neuron increased amount , abnormal
Show

 ZFA:0000242 male organism male organism decreased male fertility , abnormal
Show

 ZFA:0000303 female organism female organism increased female fertility , abnormal
Show

 ZFA:0000664 cranial nerve VII cranial nerve VII neuronal cell body mislocalised anteriorly , abnormal
Show

 ZFA:0000823 rhombomere 5 rhombomere 5 neuronal cell body mislocalised , abnormal
rhombomere 5 facial nerve motor nucleus has extra parts of type motor neuron neuron projection, abnormal
rhombomere 5 facial nerve motor nucleus increased volume , abnormal
Show

 ZFA:0000949 rhombomere 7 rhombomere 7 neuronal cell body mislocalised , abnormal
Show

 ZFA:0001032 rhombomere 4 rhombomere 4 neuronal cell body mislocalised , abnormal
rhombomere 4 facial nerve motor nucleus has extra parts of type motor neuron neuron projection, abnormal
rhombomere 4 facial nerve motor nucleus increased volume , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
whole organism semi-viable , abnormal
whole organism decreased weight , abnormal
whole organism anterior-posterior axis curved , abnormal
whole organism posterior region morphology , abnormal
whole organism decreased fertility , abnormal
whole organism decreased size , abnormal
Show

 ZFA:0001135 neural tube neural tube wholly ventralized , abnormal
Show

 ZFA:0009076 oligodendrocyte oligodendrocyte decreased amount , abnormal
Show

 ZFA:0009244 primary motor neuron primary motor neuron structure , abnormal
primary motor neuron increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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