ENSDARG00000103937


Danio rerio

Features
Gene ID: ENSDARG00000103937
  
Biological name :ndrg4
  
Synonyms : ndrg4 / NDRG family member 4
  
Possible biological names infered from orthology : Protein NDRG4 / Q8BTG7 / Q9ULP0
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 13332280
Gene end: 13381854
  
Corresponding Affymetrix probe sets: Dr.11104.1.A1_at (Zebrafish Array)   Dr.24339.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000130098
Ensembl peptide - ENSDARP00000141868
Ensembl peptide - ENSDARP00000140531
Ensembl peptide - ENSDARP00000139210
Ensembl peptide - ENSDARP00000130451
NCBI entrez gene - 692305     See in Manteia.
RefSeq - XM_005163077
RefSeq - XM_005163080
RefSeq - XM_005163081
RefSeq - XM_009297861
RefSeq - XM_021470527
RefSeq - NM_001045173
RefSeq - XM_005163079
RefSeq Peptide - NP_001038638
swissprot - A6XCT1
swissprot - A0A0R4ITZ8
swissprot - A0A0R4IRU1
swissprot - A0A0R4ICQ1
swissprot - A0A0R4IAD5
ZFIN ID - ZDB-GENE-060512-226
Ensembl - ENSDARG00000103937
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NDRG4ENSGALG00000043662Gallus gallus
 NDRG4ENSG00000103034Homo sapiens
 Ndrg4ENSMUSG00000036564Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ndrg3b / ndrg family member 3b / NDRG3* / Q9UGV2* / Q9QYF9* / NDRG family member 3* / Mus musculus N-myc downstream regulated 3 (Ndrg3), transcript variant 6, mRNA.*ENSDARG0000001005261
ndrg3a / ndrg family member 3a / NDRG3* / Q9UGV2* / Q9QYF9* / NDRG family member 3* / Mus musculus N-myc downstream regulated 3 (Ndrg3), transcript variant 6, mRNA.*ENSDARG0000001308760
ndrg2 / Q5PR98 / NDRG family member 2 / Q9UN36* / Q9QYG0* / Protein NDRG2 Protein NDRG2, N-terminally processed*ENSDARG0000001117056
ndrg1a / N-myc downstream regulated 1a / NDRG1* / Q62433* / Q92597* / Protein NDRG1 * / N-myc downstream regulated 1*ENSDARG0000003284956
ndrg1b / N-myc downstream regulated 1b / NDRG1* / Q62433* / Q92597* / Protein NDRG1 * / N-myc downstream regulated 1*ENSDARG0000001042053


Protein motifs (from Interpro)
Interpro ID Name
 IPR004142  NDRG
 IPR029058  Alpha/Beta hydrolase fold
 IPR030695  Protein NDRG4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0035050 embryonic heart tube development IMP
 biological_processGO:0045162 clustering of voltage-gated sodium channels IMP
 biological_processGO:0060038 cardiac muscle cell proliferation IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle decreased size , abnormal
cardiac ventricle cardiac muscle cell decreased amount , abnormal
Show

 ZFA:0000012 central nervous system central nervous system apoptotic , abnormal
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 ZFA:0000029 hindbrain hindbrain edematous , abnormal
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 ZFA:0000037 anatomical structure anatomical structure absent , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000114 heart heart elongated , abnormal
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 ZFA:0000175 posterior lateral line nerve posterior lateral line nerve synaptic vesicle spatial pattern , abnormal
posterior lateral line nerve synaptic vesicle aggregated , abnormal
posterior lateral line nerve axon decreased distribution , abnormal
posterior lateral line nerve node of Ranvier decreased amount , abnormal
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 ZFA:0000360 heart tube heart tube morphology , abnormal
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 ZFA:0000471 atrium atrium decreased size , abnormal
atrium dilated , abnormal
atrium extracellular matrix increased size , abnormal
atrium cardiac muscle cell decreased amount , abnormal
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 ZFA:0001094 whole organism whole organism decreased amount , abnormal
whole organism decreased width , abnormal
whole organism decreased length , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001314 posterior lateral line ganglion posterior lateral line ganglion decreased distribution , abnormal
posterior lateral line ganglion neuron decreased distribution , abnormal
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 ZFA:0001315 atrioventricular canal atrioventricular canal cardiac muscle cell mislocalised , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell decreased size , abnormal
cardiac muscle cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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