ENSG00000002834


Homo sapiens

Features
Gene ID: ENSG00000002834
  
Biological name :LASP1
  
Synonyms : LASP1 / LIM and SH3 protein 1 / Q14847
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q12
Gene start: 38869859
Gene end: 38921770
  
Corresponding Affymetrix probe sets: 200618_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000401048
Ensembl peptide - ENSP00000468664
Ensembl peptide - ENSP00000462564
Ensembl peptide - ENSP00000414803
Ensembl peptide - ENSP00000325240
Ensembl peptide - ENSP00000391897
Ensembl peptide - ENSP00000392853
NCBI entrez gene - 3927     See in Manteia.
OMIM - 602920
RefSeq - NM_001271608
RefSeq - NM_006148
RefSeq Peptide - NP_001258537
RefSeq Peptide - NP_006139
swissprot - C9J9W2
swissprot - Q14847
swissprot - A0A024R1S8
swissprot - F6S2S5
swissprot - J3KSN1
swissprot - K7ESD6
Ensembl - ENSG00000002834
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lasp1ENSDARG00000057867Danio rerio
 LASP1ENSGALG00000039299Gallus gallus
 Lasp1ENSMUSG00000038366Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NEBL / O76041 / nebuletteENSG0000007811447
NEB / P20929 / nebulinENSG0000018309138
NRAP / Q86VF7 / nebulin related anchoring proteinENSG0000019789311


Protein motifs (from Interpro)
Interpro ID Name
 IPR000900  Nebulin repeat
 IPR001452  SH3 domain
 IPR001781  Zinc finger, LIM-type
 IPR035630  Lasp1, SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport ISS
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0030864 cortical actin cytoskeleton ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005070 SH3/SH2 adaptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015075 ion transmembrane transporter activity ISS
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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