ENSG00000005059


Homo sapiens

Features
Gene ID: ENSG00000005059
  
Biological name :MCUB
  
Synonyms : MCUB / mitochondrial calcium uniporter dominant negative beta subunit / Q9NWR8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q25
Gene start: 109560205
Gene end: 109688726
  
Corresponding Affymetrix probe sets: 218802_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378145
NCBI entrez gene - 55013     See in Manteia.
RefSeq - NM_017918
RefSeq - XM_006714246
RefSeq Peptide - NP_060388
swissprot - Q9NWR8
Ensembl - ENSG00000005059
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MCUBENSGALG00000012196Gallus gallus
 McubENSMUSG00000027994Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MCU / Q8NE86 / mitochondrial calcium uniporterENSG0000015602641


Protein motifs (from Interpro)
Interpro ID Name
 IPR006769  Coiled-coil domain containing protein 109, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006851 mitochondrial calcium ion transmembrane transport IEA
 biological_processGO:0036444 calcium import into the mitochondrion IBA
 biological_processGO:0051560 mitochondrial calcium ion homeostasis IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005739 mitochondrion ISS
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031224 intrinsic component of membrane IEA
 cellular_componentGO:0031305 integral component of mitochondrial inner membrane IDA
 cellular_componentGO:0034704 calcium channel complex IEA
 cellular_componentGO:1990246 uniplex complex IDA
 molecular_functionGO:0019855 calcium channel inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial calcium ion transport
Processing of SMDT1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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