ENSMUSG00000027994


Mus musculus

Features
Gene ID: ENSMUSG00000027994
  
Biological name :Mcub
  
Synonyms : Calcium uniporter regulatory subunit MCUb, mitochondrial / Mcub / Q810S1
  
Possible biological names infered from orthology : mitochondrial calcium uniporter dominant negative beta subunit / Q9NWR8
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: G3
Gene start: 129914960
Gene end: 129970206
  
Corresponding Affymetrix probe sets: 10502156 (MoGene1.0st)   1418778_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118170
Ensembl peptide - ENSMUSP00000120660
Ensembl peptide - ENSMUSP00000029624
Ensembl peptide - ENSMUSP00000115224
NCBI entrez gene - 66815     See in Manteia.
MGI - MGI:1914065
RefSeq - XM_006501900
RefSeq - XM_011240197
RefSeq - XM_006501901
RefSeq - NM_001293644
RefSeq - NM_025779
RefSeq Peptide - NP_001280573
RefSeq Peptide - NP_080055
swissprot - Q810S1
swissprot - D6RIL8
swissprot - D6RI54
swissprot - F6SD17
Ensembl - ENSMUSG00000027994
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MCUBENSGALG00000012196Gallus gallus
 MCUBENSG00000005059Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mcu / Q3UMR5 / Calcium uniporter protein, mitochondrial / Q8NE86* / mitochondrial calcium uniporter*ENSMUSG0000000964740


Protein motifs (from Interpro)
Interpro ID Name
 IPR006769  Coiled-coil domain containing protein 109, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006851 mitochondrial calcium ion transmembrane transport IMP
 biological_processGO:0036444 calcium import into the mitochondrion IBA
 biological_processGO:0051560 mitochondrial calcium ion homeostasis IMP
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005739 mitochondrion IMP
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031224 intrinsic component of membrane IDA
 cellular_componentGO:0031305 integral component of mitochondrial inner membrane IEA
 cellular_componentGO:0034704 calcium channel complex IDA
 cellular_componentGO:1990246 uniplex complex IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019855 calcium channel inhibitor activity IDA


Pathways (from Reactome)
Pathway description
Mitochondrial calcium ion transport
Processing of SMDT1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001284 absent vibrissae "missing whiskers" [J:18378]
Show

Allelic Composition: Cbx2tm1b(KOMP)Wtsi/Cbx2+
Genetic Background: C57BL/6N-Cbx2tm1b(KOMP)Wtsi/H

 MP:0001523 impaired righting response "reduced ability or greater amount of time needed to recover from supine position" [J:25565]
Show

Allelic Composition: Cbx2tm1b(KOMP)Wtsi/Cbx2+
Genetic Background: C57BL/6N-Cbx2tm1b(KOMP)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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