ENSG00000005436


Homo sapiens

Features
Gene ID: ENSG00000005436
  
Biological name :GCFC2
  
Synonyms : GCFC2 / GC-rich sequence DNA-binding factor 2 / P16383
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p12
Gene start: 75652000
Gene end: 75710989
  
Corresponding Affymetrix probe sets: 210175_at (Human Genome U133 Plus 2.0 Array)   216305_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000475108
Ensembl peptide - ENSP00000474481
Ensembl peptide - ENSP00000475130
Ensembl peptide - ENSP00000318690
Ensembl peptide - ENSP00000386552
Ensembl peptide - ENSP00000409340
Ensembl peptide - ENSP00000415831
Ensembl peptide - ENSP00000437767
Ensembl peptide - ENSP00000474136
NCBI entrez gene - 6936     See in Manteia.
OMIM - 189901
RefSeq - XM_011533074
RefSeq - NM_001201334
RefSeq - NM_001201335
RefSeq - NM_003203
RefSeq - XM_005264520
RefSeq Peptide - NP_001188263
RefSeq Peptide - NP_001188264
RefSeq Peptide - NP_003194
swissprot - P16383
swissprot - S4R3C1
swissprot - H7C335
swissprot - S4R461
swissprot - S4R465
swissprot - C9JII4
Ensembl - ENSG00000005436
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gcfc2ENSDARG00000079020Danio rerio
 ENSGALG00000046522Gallus gallus
 ENSGALG00000044552Gallus gallus
 ENSGALG00000046148Gallus gallus
 ENSGALG00000045328Gallus gallus
 ENSGALG00000046317Gallus gallus
 ENSGALG00000046220Gallus gallus
 ENSGALG00000045250Gallus gallus
 ENSGALG00000046351Gallus gallus
 ENSGALG00000044121Gallus gallus
 ENSGALG00000046078Gallus gallus
 ENSGALG00000045927Gallus gallus
 ENSGALG00000045800Gallus gallus
 ENSGALG00000046365Gallus gallus
 ENSGALG00000016732Gallus gallus
 ENSGALG00000045708Gallus gallus
 ENSGALG00000043940Gallus gallus
 ENSGALG00000044736Gallus gallus
 ENSGALG00000044622Gallus gallus
 ENSGALG00000044143Gallus gallus
 ENSGALG00000045667Gallus gallus
 ENSGALG00000044558Gallus gallus
 Gcfc2ENSMUSG00000035125Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PAXBP1 / Q9Y5B6 / PAX3 and PAX7 binding protein 1ENSG0000015908632


Protein motifs (from Interpro)
Interpro ID Name
 IPR012890  GC-rich sequence DNA-binding factor
 IPR022783  GC-rich sequence DNA-binding factor-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0000245 spliceosomal complex assembly IMP
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated NAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0071008 U2-type post-mRNA release spliceosomal complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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