ENSG00000005981


Homo sapiens

Features
Gene ID: ENSG00000005981
  
Biological name :ASB4
  
Synonyms : ankyrin repeat and SOCS box containing 4 / ASB4 / Q9Y574
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q21.3
Gene start: 95478444
Gene end: 95540232
  
Corresponding Affymetrix probe sets: 208481_at (Human Genome U133 Plus 2.0 Array)   217228_s_at (Human Genome U133 Plus 2.0 Array)   217229_at (Human Genome U133 Plus 2.0 Array)   235619_at (Human Genome U133 Plus 2.0 Array)   237720_at (Human Genome U133 Plus 2.0 Array)   237721_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000321388
Ensembl peptide - ENSP00000397070
NCBI entrez gene - 51666     See in Manteia.
OMIM - 605761
RefSeq - XM_017012303
RefSeq - NM_016116
RefSeq - NM_145872
RefSeq Peptide - NP_665879
RefSeq Peptide - NP_057200
swissprot - Q9Y574
Ensembl - ENSG00000005981
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asb4ENSDARG00000034988Danio rerio
 ENSGALG00000009691Gallus gallus
 Asb4ENSMUSG00000042607Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASB18 / Q6ZVZ8 / ankyrin repeat and SOCS box containing 18ENSG0000018217733
ASB10 / Q8WXI3 / ankyrin repeat and SOCS box containing 10ENSG0000014692631
ASB16 / Q96NS5 / ankyrin repeat and SOCS box containing 16ENSG0000016166431


Protein motifs (from Interpro)
Interpro ID Name
 IPR001496  SOCS box domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR036036  SOCS box-like domain superfamily
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0051865 protein autoubiquitination IEA
 biological_processGO:2001214 positive regulation of vasculogenesis IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0031462 Cul2-RING ubiquitin ligase complex IEA
 cellular_componentGO:0031466 Cul5-RING ubiquitin ligase complex IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr