ENSG00000006025


Homo sapiens

Features
Gene ID: ENSG00000006025
  
Biological name :OSBPL7
  
Synonyms : OSBPL7 / oxysterol binding protein like 7 / Q9BZF2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.32
Gene start: 47807372
Gene end: 47821834
  
Corresponding Affymetrix probe sets: 208163_s_at (Human Genome U133 Plus 2.0 Array)   210344_at (Human Genome U133 Plus 2.0 Array)   227946_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000376295
Ensembl peptide - ENSP00000464624
Ensembl peptide - ENSP00000479827
Ensembl peptide - ENSP00000007414
Ensembl peptide - ENSP00000463599
NCBI entrez gene - 114881     See in Manteia.
OMIM - 606735
RefSeq - XM_017024124
RefSeq - NM_145798
RefSeq - XM_017024122
RefSeq - XM_017024123
RefSeq Peptide - NP_665741
swissprot - Q9BZF2
swissprot - J3QSC2
swissprot - J3QLK7
Ensembl - ENSG00000006025
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 osbpl7ENSDARG00000012981Danio rerio
 OSBPL7ENSGALG00000032149Gallus gallus
 Osbpl7ENSMUSG00000038534Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OSBPL3 / Q9H4L5 / oxysterol binding protein like 3ENSG0000007088252
OSBPL6 / Q9BZF3 / oxysterol binding protein like 6ENSG0000007915652
OSBP / P22059 / oxysterol binding proteinENSG0000011004825
Q9BXW6 / OSBPL1A / oxysterol binding protein like 1AENSG0000014144725
OSBP2 / Q969R2 / oxysterol binding protein 2ENSG0000018479225
OSBPL2 / Q9H1P3 / oxysterol binding protein like 2ENSG0000013070320


Protein motifs (from Interpro)
Interpro ID Name
 IPR000648  Oxysterol-binding protein
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR018494  Oxysterol-binding protein, conserved site
 IPR037239  Oxysterol-binding protein superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006699 bile acid biosynthetic process TAS
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0010506 regulation of autophagy NAS
 biological_processGO:0015918 sterol transport IEA
 biological_processGO:0071397 cellular response to cholesterol IMP
 biological_processGO:1901800 positive regulation of proteasomal protein catabolic process IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005776 autophagosome IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0097038 perinuclear endoplasmic reticulum IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015248 sterol transporter activity TAS
 molecular_functionGO:0015485 cholesterol binding IDA


Pathways (from Reactome)
Pathway description
Synthesis of bile acids and bile salts


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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