ENSG00000070882


Homo sapiens

Features
Gene ID: ENSG00000070882
  
Biological name :OSBPL3
  
Synonyms : OSBPL3 / oxysterol binding protein like 3 / Q9H4L5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p15.3
Gene start: 24796539
Gene end: 24981634
  
Corresponding Affymetrix probe sets: 209626_s_at (Human Genome U133 Plus 2.0 Array)   209627_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000386990
Ensembl peptide - ENSP00000386953
Ensembl peptide - ENSP00000403374
Ensembl peptide - ENSP00000411249
Ensembl peptide - ENSP00000407829
Ensembl peptide - ENSP00000315410
Ensembl peptide - ENSP00000379706
Ensembl peptide - ENSP00000379708
Ensembl peptide - ENSP00000386325
Ensembl peptide - ENSP00000386429
Ensembl peptide - ENSP00000386801
NCBI entrez gene - 26031     See in Manteia.
OMIM - 606732
RefSeq - XM_017011949
RefSeq - XM_005249698
RefSeq - XM_006715681
RefSeq - XM_006715682
RefSeq - XM_006715683
RefSeq - XM_006715684
RefSeq - XM_011515258
RefSeq - XM_011515259
RefSeq - XM_017011948
RefSeq - NM_015550
RefSeq - NM_145320
RefSeq - NM_145321
RefSeq - NM_145322
RefSeq Peptide - NP_663161
RefSeq Peptide - NP_663162
RefSeq Peptide - NP_056365
RefSeq Peptide - NP_663160
swissprot - Q9H4L5
swissprot - C9JEF2
swissprot - C9JZ19
swissprot - C9J8P4
Ensembl - ENSG00000070882
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 osbpl3aENSDARG00000033251Danio rerio
 osbpl3bENSDARG00000040482Danio rerio
 OSBPL3ENSGALG00000011007Gallus gallus
 Osbpl3ENSMUSG00000029822Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OSBPL6 / Q9BZF3 / oxysterol binding protein like 6ENSG0000007915658
OSBPL7 / Q9BZF2 / oxysterol binding protein like 7ENSG0000000602549
OSBP2 / Q969R2 / oxysterol binding protein 2ENSG0000018479226
OSBP / P22059 / oxysterol binding proteinENSG0000011004825
Q9BXW6 / OSBPL1A / oxysterol binding protein like 1AENSG0000014144724
OSBPL2 / Q9H1P3 / oxysterol binding protein like 2ENSG0000013070320


Protein motifs (from Interpro)
Interpro ID Name
 IPR000648  Oxysterol-binding protein
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR018494  Oxysterol-binding protein, conserved site
 IPR037239  Oxysterol-binding protein superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006699 bile acid biosynthetic process TAS
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0015918 sterol transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0032433 filopodium tip IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0097038 perinuclear endoplasmic reticulum IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015248 sterol transporter activity TAS
 molecular_functionGO:0015485 cholesterol binding IDA


Pathways (from Reactome)
Pathway description
Synthesis of bile acids and bile salts


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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