ENSMUSG00000029822


Mus musculus

Features
Gene ID: ENSMUSG00000029822
  
Biological name :Osbpl3
  
Synonyms : Osbpl3 / Oxysterol-binding protein-related protein 3 / Q9DBS9
  
Possible biological names infered from orthology : oxysterol binding protein like 3 / Q9H4L5
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: B2.3
Gene start: 50293330
Gene end: 50456201
  
Corresponding Affymetrix probe sets: 10544660 (MoGene1.0st)   1428484_at (Mouse Genome 430 2.0 Array)   1438724_at (Mouse Genome 430 2.0 Array)   1446746_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000087473
Ensembl peptide - ENSMUSP00000110110
Ensembl peptide - ENSMUSP00000145249
Ensembl peptide - ENSMUSP00000144934
Ensembl peptide - ENSMUSP00000114472
Ensembl peptide - ENSMUSP00000110112
Ensembl peptide - ENSMUSP00000071643
NCBI entrez gene - 71720     See in Manteia.
MGI - MGI:1918970
RefSeq - XM_006506631
RefSeq - XM_006506630
RefSeq - XM_006506628
RefSeq - XM_006506635
RefSeq - XM_006506634
RefSeq - XM_006506633
RefSeq - NM_001163645
RefSeq - NM_027881
RefSeq - XM_011241468
RefSeq - XM_006506636
RefSeq Peptide - NP_082157
RefSeq Peptide - NP_001157117
RefSeq Peptide - NP_001334142
swissprot - Q9DBS9
swissprot - D3Z194
swissprot - A0A0N4SV33
swissprot - F8WH20
swissprot - A0A0N4SVU7
swissprot - D3YTT6
swissprot - D3YVF7
Ensembl - ENSMUSG00000029822
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 osbpl3aENSDARG00000033251Danio rerio
 osbpl3bENSDARG00000040482Danio rerio
 OSBPL3ENSGALG00000011007Gallus gallus
 OSBPL3ENSG00000070882Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Osbpl6 / Q8BXR9 / Oxysterol-binding protein-related protein 6 / Q9BZF3* / oxysterol binding protein like 6*ENSMUSG0000004235958
Osbpl7 / oxysterol binding protein like 7 / Q9BZF2*ENSMUSG0000003853450
Osbp / Q3B7Z2 / Oxysterol-binding protein 1 / P22059* / oxysterol binding protein*ENSMUSG0000002468726
Osbp2 / Q5QNQ6 / Oxysterol-binding protein 2 / Q969R2*ENSMUSG0000002043525
Q91XL9 / Osbpl1a / Oxysterol-binding protein-related protein 1 / Q9BXW6* / oxysterol binding protein like 1A*ENSMUSG0000004425224
Osbpl2 / Q8BX94 / Oxysterol-binding protein-related protein 2 / Q9H1P3* / oxysterol binding protein like 2*ENSMUSG0000003905020


Protein motifs (from Interpro)
Interpro ID Name
 IPR000648  Oxysterol-binding protein
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR018494  Oxysterol-binding protein, conserved site
 IPR037239  Oxysterol-binding protein superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0032433 filopodium tip IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0097038 perinuclear endoplasmic reticulum IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015485 cholesterol binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of bile acids and bile salts


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000062 increased bone density "increased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]
Show

Allelic Composition: Izumo1rtm2a(KOMP)Wtsi/Izumo1rtm2a(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm2a(KOMP)Wtsi/Wtsi

 MP:0003442 decreased circulating glycerol level "lower than normal concentration of glycerol in the blood" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Izumo1rtm2a(KOMP)Wtsi/Izumo1rtm2a(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm2a(KOMP)Wtsi/Wtsi

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Izumo1rtm2a(KOMP)Wtsi/Izumo1rtm2a(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm2a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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