ENSMUSG00000044252


Mus musculus

Features
Gene ID: ENSMUSG00000044252
  
Biological name :Osbpl1a
  
Synonyms : Osbpl1a / Oxysterol-binding protein-related protein 1 / Q91XL9
  
Possible biological names infered from orthology : oxysterol binding protein like 1A / Q9BXW6
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: A1
Gene start: 12755314
Gene end: 12941841
  
Corresponding Affymetrix probe sets: 10457546 (MoGene1.0st)   1416823_a_at (Mouse Genome 430 2.0 Array)   1460192_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114913
Ensembl peptide - ENSMUSP00000113914
Ensembl peptide - ENSMUSP00000120439
Ensembl peptide - ENSMUSP00000122967
Ensembl peptide - ENSMUSP00000122291
Ensembl peptide - ENSMUSP00000073957
Ensembl peptide - ENSMUSP00000112681
Ensembl peptide - ENSMUSP00000112895
Ensembl peptide - ENSMUSP00000113268
Ensembl peptide - ENSMUSP00000113357
Ensembl peptide - ENSMUSP00000113491
Ensembl peptide - ENSMUSP00000113735
Ensembl peptide - ENSMUSP00000113841
NCBI entrez gene - 64291     See in Manteia.
MGI - MGI:1927551
RefSeq - XM_017317965
RefSeq - NM_001252493
RefSeq - NM_207530
RefSeq - XM_006526141
RefSeq - XM_006526142
RefSeq - XM_006526143
RefSeq - XM_006526144
RefSeq - XM_006526147
RefSeq - XM_006526148
RefSeq - XM_017317960
RefSeq - XM_017317961
RefSeq - XM_017317962
RefSeq - XM_017317963
RefSeq - XM_017317964
RefSeq - NM_001252489
RefSeq - NM_001252490
RefSeq - NM_001252491
RefSeq - NM_001252492
RefSeq Peptide - NP_001239422
RefSeq Peptide - NP_997413
RefSeq Peptide - NP_001239418
RefSeq Peptide - NP_001239419
RefSeq Peptide - NP_001239420
RefSeq Peptide - NP_001239421
swissprot - D3YZ66
swissprot - Q8K2D2
swissprot - D3Z7I9
swissprot - D3Z754
swissprot - Q3V156
swissprot - D6RDE4
swissprot - Q91XL9
Ensembl - ENSMUSG00000044252
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01084566.1ENSDARG00000053746Danio rerio
 osbpl1aENSDARG00000105147Danio rerio
 OSBPL1AENSGALG00000015086Gallus gallus
 Q9BXW6ENSG00000141447Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Osbpl2 / Q8BX94 / Oxysterol-binding protein-related protein 2 / Q9H1P3* / oxysterol binding protein like 2*ENSMUSG0000003905034
Osbp2 / Q5QNQ6 / Oxysterol-binding protein 2 / Q969R2*ENSMUSG0000002043525
Osbpl6 / Q8BXR9 / Oxysterol-binding protein-related protein 6 / Q9BZF3* / oxysterol binding protein like 6*ENSMUSG0000004235925
Osbp / Q3B7Z2 / Oxysterol-binding protein 1 / P22059* / oxysterol binding protein*ENSMUSG0000002468724
Osbpl7 / oxysterol binding protein like 7 / Q9BZF2*ENSMUSG0000003853423
Osbpl3 / Q9DBS9 / Oxysterol-binding protein-related protein 3 / Q9H4L5* / oxysterol binding protein like 3*ENSMUSG0000002982223


Protein motifs (from Interpro)
Interpro ID Name
 IPR000648  Oxysterol-binding protein
 IPR001849  Pleckstrin homology domain
 IPR002110  Ankyrin repeat
 IPR011993  PH-like domain superfamily
 IPR018494  Oxysterol-binding protein, conserved site
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR037239  Oxysterol-binding protein superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome ISS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015485 cholesterol binding ISO


Pathways (from Reactome)
Pathway description
Synthesis of bile acids and bile salts
MHC class II antigen presentation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000044252 Q91XL9 / Osbpl1a / Oxysterol-binding protein-related protein 1 / Q9BXW6* / oxysterol binding protein like 1A*  / complex
 ENSMUSG00000038195 Rilp / Q5ND29 / Rab interacting lysosomal protein / Q96NA2*  / complex
 ENSMUSG00000079477 Rab7 / P51150 / RAB7, member RAS oncogene family / RAB7A* / P51149* / RAB7A, member RAS oncogene family*  / complex






 

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contact: otassy@igbmc.fr