ENSG00000006715


Homo sapiens

Features
Gene ID: ENSG00000006715
  
Biological name :VPS41
  
Synonyms : P49754 / VPS41 / VPS41, HOPS complex subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p14.1
Gene start: 38722963
Gene end: 38932394
  
Corresponding Affymetrix probe sets: 203106_s_at (Human Genome U133 Plus 2.0 Array)   210849_s_at (Human Genome U133 Plus 2.0 Array)   235625_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391980
Ensembl peptide - ENSP00000412974
Ensembl peptide - ENSP00000411919
Ensembl peptide - ENSP00000407835
Ensembl peptide - ENSP00000398584
Ensembl peptide - ENSP00000395410
Ensembl peptide - ENSP00000265745
Ensembl peptide - ENSP00000309457
Ensembl peptide - ENSP00000379297
NCBI entrez gene - 27072     See in Manteia.
OMIM - 605485
RefSeq - NM_014396
RefSeq - NM_080631
RefSeq Peptide - NP_055211
RefSeq Peptide - NP_542198
swissprot - H7BZX6
swissprot - H7C0K2
swissprot - C9JZ11
swissprot - P49754
swissprot - C9JU58
swissprot - C9J3F8
swissprot - C9J2U9
swissprot - H7BXH3
Ensembl - ENSG00000006715
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vps41ENSDARG00000063573Danio rerio
 VPS41ENSGALG00000031635Gallus gallus
 Vps41ENSMUSG00000041236Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000547  Clathrin, heavy chain/VPS, 7-fold repeat
 IPR001841  Zinc finger, RING-type
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016902  Vacuolar protein sorting-associated protein 41
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006623 protein targeting to vacuole IBA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0008333 endosome to lysosome transport IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0034058 endosomal vesicle fusion IMP
 biological_processGO:0035542 regulation of SNARE complex assembly IBA
 biological_processGO:0042144 vacuole fusion, non-autophagic IBA
 biological_processGO:0045055 regulated exocytosis IEA
 biological_processGO:0046907 intracellular transport IEA
 biological_processGO:1902774 late endosome to lysosome transport IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005798 Golgi-associated vesicle IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030123 AP-3 adaptor complex IDA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0030897 HOPS complex IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031902 late endosome membrane IDA
 cellular_componentGO:0033263 CORVET complex IBA
 cellular_componentGO:0071439 clathrin complex IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043621 protein self-association IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051020 GTPase binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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