ENSG00000006757


Homo sapiens

Features
Gene ID: ENSG00000006757
  
Biological name :PNPLA4
  
Synonyms : P41247 / patatin like phospholipase domain containing 4 / PNPLA4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: p22.31
Gene start: 7898247
Gene end: 7927739
  
Corresponding Affymetrix probe sets: 209739_s_at (Human Genome U133 Plus 2.0 Array)   209740_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000415245
Ensembl peptide - ENSP00000443157
Ensembl peptide - ENSP00000370430
Ensembl peptide - ENSP00000406698
NCBI entrez gene - 8228     See in Manteia.
OMIM - 300102
RefSeq - XM_011545588
RefSeq - NM_001142389
RefSeq - NM_001172672
RefSeq - NM_004650
RefSeq Peptide - NP_001135861
RefSeq Peptide - NP_001166143
RefSeq Peptide - NP_004641
swissprot - A0A024RBU8
swissprot - C9IZF6
swissprot - P41247
Ensembl - ENSG00000006757
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pnpla4ENSDARG00000069834Danio rerio
 PNPLA4ENSGALG00000016618Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PNPLA2 / Q96AD5 / patatin like phospholipase domain containing 2ENSG0000017766636
PNPLA3 / Q9NST1 / patatin like phospholipase domain containing 3ENSG0000010034434
PNPLA1 / Q8N8W4 / patatin like phospholipase domain containing 1ENSG0000018031632
PNPLA5 / Q7Z6Z6 / patatin like phospholipase domain containing 5ENSG0000010034129


Protein motifs (from Interpro)
Interpro ID Name
 IPR002641  Patatin-like phospholipase domain
 IPR016035  Acyl transferase/acyl hydrolase/lysophospholipase
 IPR033562  Patatin-like phospholipase domain-containing protein
 IPR033902  Patatin-like phospholipase domain-containing protein 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0019433 triglyceride catabolic process IBA
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:0055088 lipid homeostasis IBA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005811 lipid droplet IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IBA
 molecular_functionGO:0004806 triglyceride lipase activity EXP
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0050253 retinyl-palmitate esterase activity EXP


Pathways (from Reactome)
Pathway description
Triglyceride catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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