ENSG00000007038


Homo sapiens

Features
Gene ID: ENSG00000007038
  
Biological name :PRSS21
  
Synonyms : PRSS21 / Q9Y6M0 / serine protease 21
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 2817180
Gene end: 2826304
  
Corresponding Affymetrix probe sets: 220051_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000460417
Ensembl peptide - ENSP00000459664
Ensembl peptide - ENSP00000460351
Ensembl peptide - ENSP00000005995
Ensembl peptide - ENSP00000407741
Ensembl peptide - ENSP00000458341
NCBI entrez gene - 10942     See in Manteia.
OMIM - 608159
RefSeq - XM_017022878
RefSeq - NM_001270452
RefSeq - NM_006799
RefSeq - NM_144956
RefSeq - NM_144957
RefSeq - XM_017022875
RefSeq - XM_017022876
RefSeq - XM_017022877
RefSeq Peptide - NP_659205
RefSeq Peptide - NP_659206
RefSeq Peptide - NP_006790
RefSeq Peptide - NP_001257381
swissprot - Q9Y6M0
swissprot - I3L0U2
swissprot - I3L2G7
swissprot - I3L3C7
swissprot - I3L3F7
Ensembl - ENSG00000007038
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU571315.2ENSDARG00000101956Danio rerio
 CU571315.3ENSDARG00000101990Danio rerio
 prss60.1ENSDARG00000070713Danio rerio
 prss60.2ENSDARG00000055644Danio rerio
 prss60.3ENSDARG00000070710Danio rerio
 si:ch73-182e20.4ENSDARG00000102727Danio rerio
 si:dkey-16l2.17ENSDARG00000027196Danio rerio
 si:dkey-32n7.7ENSDARG00000063444Danio rerio
 si:dkey-32n7.9ENSDARG00000071841Danio rerio
 si:dkeyp-93a5.2ENSDARG00000052064Danio rerio
 si:dkeyp-93a5.2ENSDARG00000100953Danio rerio
 si:dkeyp-93a5.3ENSDARG00000096975Danio rerio
 zgc:100868ENSDARG00000004748Danio rerio
 zgc:112038ENSDARG00000046140Danio rerio
 zgc:123217ENSDARG00000059026Danio rerio
 zgc:123295ENSDARG00000056324Danio rerio
 zgc:153968ENSDARG00000061858Danio rerio
 zgc:163079ENSDARG00000056773Danio rerio
 zgc:165423ENSDARG00000052905Danio rerio
 zgc:92313ENSDARG00000040513Danio rerio
 Prss21ENSMUSG00000024116Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRSS41 / Q7RTY9 / serine protease 41ENSG0000021514853
TPSG1 / Q9NRR2 / tryptase gamma 1ENSG0000011617641
PRSS8 / Q16651 / serine protease 8ENSG0000005234439
PRSS48 / Q7RTY5 / serine protease 48ENSG0000018909938
PRSS27 / Q9BQR3 / serine protease 27ENSG0000017238238
PRSS33 / Q8NF86 / serine protease 33ENSG0000010335534
PRSS22 / Q9GZN4 / serine protease 22ENSG0000000500133
A1L453 / PRSS38 / serine protease 38ENSG0000018588832
PRSS42 / Q7Z5A4 / serine protease 42ENSG0000017805531
PRSS45 / Q7RTY3 / serine protease 45ENSG0000018808624
AC109583.3ENSG0000028467211


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site
 IPR034380  Testisin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007283 spermatogenesis IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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