ENSG00000008513


Homo sapiens

Features
Gene ID: ENSG00000008513
  
Biological name :ST3GAL1
  
Synonyms : Q11201 / ST3 beta-galactoside alpha-2,3-sialyltransferase 1 / ST3GAL1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q24.22
Gene start: 133454848
Gene end: 133571940
  
Corresponding Affymetrix probe sets: 208322_s_at (Human Genome U133 Plus 2.0 Array)   225033_at (Human Genome U133 Plus 2.0 Array)   225034_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000414073
Ensembl peptide - ENSP00000427720
Ensembl peptide - ENSP00000430515
Ensembl peptide - ENSP00000430135
Ensembl peptide - ENSP00000429936
Ensembl peptide - ENSP00000429638
Ensembl peptide - ENSP00000428540
Ensembl peptide - ENSP00000427786
NCBI entrez gene - 6482     See in Manteia.
OMIM - 607187
RefSeq - NM_173344
RefSeq - XM_017013737
RefSeq - XM_017013736
RefSeq - XM_011517225
RefSeq - XM_006716617
RefSeq - XM_005251025
RefSeq - NM_003033
RefSeq Peptide - NP_003024
RefSeq Peptide - NP_775479
swissprot - E5RH34
swissprot - Q11201
swissprot - A0A024R9L6
swissprot - E5RG72
swissprot - E5RGI3
swissprot - E5RGL4
swissprot - E5RHV6
Ensembl - ENSG00000008513
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 st3gal1ENSDARG00000079654Danio rerio
 st3gal1lENSDARG00000079310Danio rerio
 st3gal1l3ENSDARG00000099289Danio rerio
 Q11200ENSGALG00000037773Gallus gallus
 P54751ENSMUSG00000013846Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q16842 / ST3GAL2 / ST3 beta-galactoside alpha-2,3-sialyltransferase 2ENSG0000015735048
Q9NSC7 / ST6GALNAC1 / ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1ENSG0000007052625
Q9UJ37 / ST6GALNAC2 / ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2ENSG0000007073124
Q11206 / ST3GAL4 / ST3 beta-galactoside alpha-2,3-sialyltransferase 4ENSG0000011008023
Q9UNP4 / ST3GAL5 / ST3 beta-galactoside alpha-2,3-sialyltransferase 5ENSG0000011552522
Q11203 / ST3GAL3 / ST3 beta-galactoside alpha-2,3-sialyltransferase 3ENSG0000012609122
Q9Y274 / ST3GAL6 / ST3 beta-galactoside alpha-2,3-sialyltransferase 6ENSG0000006422520


Protein motifs (from Interpro)
Interpro ID Name
 IPR001675  Glycosyl transferase family 29
 IPR012163  Sialyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006054 N-acetylneuraminate metabolic process ISS
 biological_processGO:0006464 cellular protein modification process TAS
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006487 protein N-linked glycosylation ISS
 biological_processGO:0009311 oligosaccharide metabolic process IBA
 biological_processGO:0016266 O-glycan processing TAS
 biological_processGO:0018146 keratan sulfate biosynthetic process TAS
 biological_processGO:0018279 protein N-linked glycosylation via asparagine IBA
 biological_processGO:0097503 sialylation ISS
 cellular_componentGO:0000139 Golgi membrane IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity IDA
 molecular_functionGO:0008373 sialyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis
Sialic acid metabolism
Termination of O-glycan biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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