ENSMUSG00000013846


Mus musculus

Features
Gene ID: ENSMUSG00000013846
  
Biological name :St3gal1
  
Synonyms : P54751 / ST3 beta-galactoside alpha-2,3-sialyltransferase 1 / St3gal1
  
Possible biological names infered from orthology : Q11201
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: D2
Gene start: 67102875
Gene end: 67176830
  
Corresponding Affymetrix probe sets: 10429160 (MoGene1.0st)   1418946_at (Mouse Genome 430 2.0 Array)   1441216_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000090307
Ensembl peptide - ENSMUSP00000154853
Ensembl peptide - ENSMUSP00000155359
NCBI entrez gene - 20442     See in Manteia.
MGI - MGI:98304
RefSeq - XM_011245529
RefSeq - NM_009177
RefSeq - XM_006520664
RefSeq - XM_006520665
RefSeq Peptide - NP_033203
swissprot - P54751
swissprot - Q544T4
Ensembl - ENSMUSG00000013846
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 st3gal1ENSDARG00000079654Danio rerio
 st3gal1lENSDARG00000079310Danio rerio
 st3gal1l3ENSDARG00000099289Danio rerio
 Q11200ENSGALG00000037773Gallus gallus
 Q11201ENSG00000008513Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q11204 / St3gal2 / CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 / Q16842* / ST3 beta-galactoside alpha-2,3-sialyltransferase 2*ENSMUSG0000003174948
P70277 / St6galnac2 / ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 / Q9UJ37* / ST6 N-acetylgalactosaminide alpha-2,6-sialylt...ENSMUSG0000005728625
Q9QZ39 / St6galnac1 / Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 / Q9NSC7* / ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1*ENSMUSG0000000958824
P97325 / St3gal3 / CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase / Q11203* / ST3 beta-galactoside alpha-2,3-sialyltransferase 3*ENSMUSG0000002853823
Q91Y74 / St3gal4 / ST3 beta-galactoside alpha-2,3-sialyltransferase 4 / Q11206*ENSMUSG0000003203822
Q8VIB3 / St3gal6 / Mus musculus ST3 beta-galactoside alpha-2,3-sialyltransferase 6 (St3gal6), transcript variant 2, mRNA. / Q9Y274* / ST3 beta-galactoside alpha-2,3-sialyltransferase 6*ENSMUSG0000002274722
O88829 / St3gal5 / Lactosylceramide alpha-2,3-sialyltransferase / Q9UNP4* / ST3 beta-galactoside alpha-2,3-sialyltransferase 5*ENSMUSG0000005609121


Protein motifs (from Interpro)
Interpro ID Name
 IPR001675  Glycosyl transferase family 29
 IPR012163  Sialyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006054 N-acetylneuraminate metabolic process ISS
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006486 protein glycosylation IMP
 biological_processGO:0006487 protein N-linked glycosylation ISS
 biological_processGO:0009311 oligosaccharide metabolic process IBA
 biological_processGO:0018279 protein N-linked glycosylation via asparagine IBA
 biological_processGO:0097503 sialylation ISS
 cellular_componentGO:0000139 Golgi membrane IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 molecular_functionGO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity ISO
 molecular_functionGO:0008373 sialyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis
Sialic acid metabolism
Termination of O-glycan biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rb1tm1Tyj/Rb1tm1Tyj,Tg(Rb1)1Blg/0
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0008079 decreased CD8-positive T cell number "reduction in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Efnb1tm4.2Sor/Efnb1+
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Clec10atm1Hed/Clec10a+,St3gal1tm1Jxm/St3gal1tm1Jxm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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