ENSG00000110080


Homo sapiens

Features
Gene ID: ENSG00000110080
  
Biological name :ST3GAL4
  
Synonyms : Q11206 / ST3 beta-galactoside alpha-2,3-sialyltransferase 4 / ST3GAL4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q24.2
Gene start: 126355640
Gene end: 126440344
  
Corresponding Affymetrix probe sets: 203759_at (Human Genome U133 Plus 2.0 Array)   215710_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000432929
Ensembl peptide - ENSP00000433318
Ensembl peptide - ENSP00000436047
Ensembl peptide - ENSP00000434756
Ensembl peptide - ENSP00000434668
Ensembl peptide - ENSP00000434349
Ensembl peptide - ENSP00000433989
Ensembl peptide - ENSP00000433495
Ensembl peptide - ENSP00000227495
Ensembl peptide - ENSP00000348451
Ensembl peptide - ENSP00000376437
Ensembl peptide - ENSP00000394354
Ensembl peptide - ENSP00000399444
Ensembl peptide - ENSP00000431170
Ensembl peptide - ENSP00000432424
Ensembl peptide - ENSP00000432647
NCBI entrez gene - 6484     See in Manteia.
OMIM - 104240
RefSeq - XM_017018134
RefSeq - NM_001254757
RefSeq - NM_001254758
RefSeq - NM_001254759
RefSeq - NM_001348399
RefSeq - NM_001348400
RefSeq - NM_006278
RefSeq Peptide - NP_001335328
RefSeq Peptide - NP_006269
RefSeq Peptide - NP_001241686
RefSeq Peptide - NP_001241687
RefSeq Peptide - NP_001241688
RefSeq Peptide - NP_001335329
swissprot - E9PMC7
swissprot - E9PKJ2
swissprot - E9PPJ6
swissprot - E9PNJ9
swissprot - Q11206
swissprot - Q6IBE6
swissprot - E9PQZ2
swissprot - E9PN64
Ensembl - ENSG00000110080
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 st3gal4ENSDARG00000041006Danio rerio
 ST3GAL4ENSGALG00000029747Gallus gallus
 Q91Y74ENSMUSG00000032038Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q11203 / ST3GAL3 / ST3 beta-galactoside alpha-2,3-sialyltransferase 3ENSG0000012609138
Q9Y274 / ST3GAL6 / ST3 beta-galactoside alpha-2,3-sialyltransferase 6ENSG0000006422535
Q9UNP4 / ST3GAL5 / ST3 beta-galactoside alpha-2,3-sialyltransferase 5ENSG0000011552531
Q16842 / ST3GAL2 / ST3 beta-galactoside alpha-2,3-sialyltransferase 2ENSG0000015735024
Q11201 / ST3GAL1 / ST3 beta-galactoside alpha-2,3-sialyltransferase 1ENSG0000000851323
Q9NSC7 / ST6GALNAC1 / ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1ENSG0000007052623
Q9UJ37 / ST6GALNAC2 / ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2ENSG0000007073121


Protein motifs (from Interpro)
Interpro ID Name
 IPR001675  Glycosyl transferase family 29
 IPR012163  Sialyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IDA
 biological_processGO:0009101 glycoprotein biosynthetic process IDA
 biological_processGO:0009247 glycolipid biosynthetic process IDA
 biological_processGO:0009311 oligosaccharide metabolic process IBA
 biological_processGO:0009312 oligosaccharide biosynthetic process IDA
 biological_processGO:0016266 O-glycan processing TAS
 biological_processGO:0018146 keratan sulfate biosynthetic process TAS
 biological_processGO:0018279 protein N-linked glycosylation via asparagine IBA
 biological_processGO:0030259 lipid glycosylation IDA
 biological_processGO:0050890 cognition IMP
 biological_processGO:0097503 sialylation IDA
 biological_processGO:1990743 protein sialylation IDA
 cellular_componentGO:0000139 Golgi membrane IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity IDA
 molecular_functionGO:0008373 sialyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0047288 monosialoganglioside sialyltransferase activity IDA


Pathways (from Reactome)
Pathway description
Pre-NOTCH Processing in Golgi
Keratan sulfate biosynthesis
Sialic acid metabolism
N-Glycan antennae elongation
Termination of O-glycan biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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