ENSG00000008735


Homo sapiens

Features
Gene ID: ENSG00000008735
  
Biological name :MAPK8IP2
  
Synonyms : MAPK8IP2 / mitogen-activated protein kinase 8 interacting protein 2 / Q13387
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.33
Gene start: 50600685
Gene end: 50613981
  
Corresponding Affymetrix probe sets: 1556001_at (Human Genome U133 Plus 2.0 Array)   205050_s_at (Human Genome U133 Plus 2.0 Array)   208603_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000330572
NCBI entrez gene - 23542     See in Manteia.
OMIM - 607755
RefSeq - XM_011530681
RefSeq - NM_012324
RefSeq - XM_011530679
RefSeq - XM_011530680
RefSeq Peptide - NP_036456
swissprot - Q13387
Ensembl - ENSG00000008735
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mapk8ip2ENSDARG00000063157Danio rerio
 Q9ERE9ENSMUSG00000022619Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UQF2 / MAPK8IP1 / mitogen-activated protein kinase 8 interacting protein 1ENSG0000012165333


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR035637  JIP2, SH3 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001662 behavioral fear response IEA
 biological_processGO:0007172 signal complex assembly TAS
 biological_processGO:0007254 JNK cascade IEA
 biological_processGO:0007617 mating behavior IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IEA
 biological_processGO:0035176 social behavior IEA
 biological_processGO:0046328 regulation of JNK cascade IDA
 biological_processGO:0046958 nonassociative learning IEA
 biological_processGO:0048813 dendrite morphogenesis IEA
 biological_processGO:0051966 regulation of synaptic transmission, glutamatergic IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:2000310 regulation of NMDA receptor activity IEA
 biological_processGO:2000311 regulation of AMPA receptor activity IEA
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0001540 amyloid-beta binding NAS
 molecular_functionGO:0005078 MAP-kinase scaffold activity NAS
 molecular_functionGO:0005198 structural molecule activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019894 kinesin binding IEA
 molecular_functionGO:0019901 protein kinase binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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