ENSG00000011007


Homo sapiens

Features
Gene ID: ENSG00000011007
  
Biological name :ELOA
  
Synonyms : ELOA / elongin A / Q14241
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.11
Gene start: 23743155
Gene end: 23762059
  
Corresponding Affymetrix probe sets: 1570625_at (Human Genome U133 Plus 2.0 Array)   1570627_at (Human Genome U133 Plus 2.0 Array)   202818_s_at (Human Genome U133 Plus 2.0 Array)   202819_s_at (Human Genome U133 Plus 2.0 Array)   213604_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000476781
Ensembl peptide - ENSP00000484196
Ensembl peptide - ENSP00000395574
NCBI entrez gene - 6924     See in Manteia.
OMIM - 600786
RefSeq - NM_003198
RefSeq Peptide - NP_003189
swissprot - A0A024RAC6
swissprot - Q14241
Ensembl - ENSG00000011007
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eloaENSDARG00000102365Danio rerio
 TCEB3ENSGALG00000034625Gallus gallus
 EloaENSMUSG00000028668Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ELOA2 / Q8IYF1 / elongin A2ENSG0000020618143
ELOA3 / Q8NG57 / elongin A3ENSG0000018379134
A6NLF2 / ELOA3D / elongin A3 family member DENSG0000027474434
ELOA3B / Q3SY89 / elongin A3 family member BENSG0000027867434
ELOA3C / elongin A3 family member CENSG0000027555325


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR003617  Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type
 IPR010684  RNA polymerase II transcription factor SIII, subunit A
 IPR017923  Transcription factor IIS, N-terminal
 IPR035441  TFIIS/LEDGF domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter TAS
 biological_processGO:0006414 translational elongation IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0070449 elongin complex IBA
 molecular_functionGO:0003746 translation elongation factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000103363 ELOB / Q15370 / elongin B  / complex / reaction
 ENSG00000154582 ELOC / Q15369 / elongin C  / complex / reaction






 

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