ENSG00000011028


Homo sapiens

Features
Gene ID: ENSG00000011028
  
Biological name :MRC2
  
Synonyms : mannose receptor C type 2 / MRC2 / Q9UBG0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q23.2
Gene start: 62627401
Gene end: 62693597
  
Corresponding Affymetrix probe sets: 209280_at (Human Genome U133 Plus 2.0 Array)   37408_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000461968
Ensembl peptide - ENSP00000463968
Ensembl peptide - ENSP00000307513
Ensembl peptide - ENSP00000400445
NCBI entrez gene - 9902     See in Manteia.
OMIM - 612264
RefSeq - NM_006039
RefSeq - XM_011525543
RefSeq Peptide - NP_006030
swissprot - J3QQZ6
swissprot - E7EME3
swissprot - Q9UBG0
swissprot - J3KRF1
Ensembl - ENSG00000011028
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mrc2ENSDARG00000078135Danio rerio
 MRC2ENSGALG00000000461Gallus gallus
 Mrc2ENSMUSG00000020695Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLA2R1 / Q13018 / phospholipase A2 receptor 1ENSG0000015324633
MRC1 / P22897 / mannose receptor C-type 1ENSG0000026031432
LY75-CD302 / LY75-CD302 readthroughENSG0000024867230
LY75 / O60449 / lymphocyte antigen 75ENSG0000005421930


Protein motifs (from Interpro)
Interpro ID Name
 IPR000562  Fibronectin type II domain
 IPR000772  Ricin B, lectin domain
 IPR001304  C-type lectin-like
 IPR013806  Kringle-like fold
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR033989  CD209-like, C-type lectin-like domain
 IPR035992  Ricin B-like lectins
 IPR036943  Fibronectin type II domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation HDA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0030574 collagen catabolic process IDA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005518 collagen binding IDA
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Cross-presentation of soluble exogenous antigens (endosomes)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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