ENSG00000153246


Homo sapiens

Features
Gene ID: ENSG00000153246
  
Biological name :PLA2R1
  
Synonyms : phospholipase A2 receptor 1 / PLA2R1 / Q13018
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q24.2
Gene start: 159932006
Gene end: 160062610
  
Corresponding Affymetrix probe sets: 207415_at (Human Genome U133 Plus 2.0 Array)   210194_at (Human Genome U133 Plus 2.0 Array)   235746_s_at (Human Genome U133 Plus 2.0 Array)   240039_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000283243
Ensembl peptide - ENSP00000376524
NCBI entrez gene - 22925     See in Manteia.
OMIM - 604939
RefSeq - XM_017003600
RefSeq - NM_001007267
RefSeq - NM_001195641
RefSeq - NM_007366
RefSeq - XM_005246392
RefSeq - XM_011510820
RefSeq - XM_017003598
RefSeq - XM_017003599
RefSeq Peptide - NP_001182570
RefSeq Peptide - NP_031392
RefSeq Peptide - NP_001007268
swissprot - Q13018
Ensembl - ENSG00000153246
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pla2r1ENSDARG00000077474Danio rerio
 PLA2R1ENSGALG00000011149Gallus gallus
 Pla2r1ENSMUSG00000054580Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MRC2 / Q9UBG0 / mannose receptor C type 2ENSG0000001102834
LY75 / O60449 / lymphocyte antigen 75ENSG0000005421934
LY75-CD302 / LY75-CD302 readthroughENSG0000024867234
MRC1 / P22897 / mannose receptor C-type 1ENSG0000026031429


Protein motifs (from Interpro)
Interpro ID Name
 IPR000562  Fibronectin type II domain
 IPR000772  Ricin B, lectin domain
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR035992  Ricin B-like lectins
 IPR036943  Fibronectin type II domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001816 cytokine production IMP
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator IMP
 biological_processGO:0072593 reactive oxygen species metabolic process IDA
 biological_processGO:0090238 positive regulation of arachidonic acid secretion ISS
 biological_processGO:0090399 replicative senescence IMP
 biological_processGO:0090403 oxidative stress-induced premature senescence IMP
 biological_processGO:1900138 negative regulation of phospholipase A2 activity ISS
 biological_processGO:1900139 negative regulation of arachidonic acid secretion ISS
 cellular_componentGO:0005576 extracellular region ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0043274 phospholipase binding IEA


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PC
Acyl chain remodelling of PS
Acyl chain remodelling of PE
Acyl chain remodelling of PI
Acyl chain remodelling of PG
Synthesis of PA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr