ENSG00000260314


Homo sapiens

Features
Gene ID: ENSG00000260314
  
Biological name :MRC1
  
Synonyms : mannose receptor C-type 1 / MRC1 / P22897
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: p12.33
Gene start: 17809344
Gene end: 17911170
  
Corresponding Affymetrix probe sets: 204438_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000455897
NCBI entrez gene - 4360     See in Manteia.
OMIM - 153618
RefSeq - NM_002438
RefSeq Peptide - NP_002429
swissprot - P22897
Ensembl - ENSG00000260314
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mrc1aENSDARG00000102100Danio rerio
 MMR1L1ENSGALG00000027765Gallus gallus
 MMR1L2ENSGALG00000028357Gallus gallus
 MMR1L3ENSGALG00000008638Gallus gallus
 MMR1L4ENSGALG00000028304Gallus gallus
 MRC1ENSGALG00000008629Gallus gallus
 Mrc1ENSMUSG00000026712Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MRC2 / Q9UBG0 / mannose receptor C type 2ENSG0000001102833
PLA2R1 / Q13018 / phospholipase A2 receptor 1ENSG0000015324629
LY75 / O60449 / lymphocyte antigen 75ENSG0000005421927
LY75-CD302 / LY75-CD302 readthroughENSG0000024867227


Protein motifs (from Interpro)
Interpro ID Name
 IPR000562  Fibronectin type II domain
 IPR000772  Ricin B, lectin domain
 IPR001304  C-type lectin-like
 IPR013806  Kringle-like fold
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR035992  Ricin B-like lectins
 IPR036943  Fibronectin type II domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006898 receptor-mediated endocytosis IDA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071346 cellular response to interferon-gamma IEA
 biological_processGO:0071353 cellular response to interleukin-4 IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0001618 virus receptor activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005537 mannose binding TAS
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Cross-presentation of soluble exogenous antigens (endosomes)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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