ENSG00000013288


Homo sapiens

Features
Gene ID: ENSG00000013288
  
Biological name :MAN2B2
  
Synonyms : MAN2B2 / mannosidase alpha class 2B member 2 / Q9Y2E5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p16.1
Gene start: 6575175
Gene end: 6623362
  
Corresponding Affymetrix probe sets: 214703_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000426273
Ensembl peptide - ENSP00000285599
Ensembl peptide - ENSP00000423129
NCBI entrez gene - 23324     See in Manteia.
RefSeq - NM_015274
RefSeq - NM_001292038
RefSeq Peptide - NP_001278967
RefSeq Peptide - NP_056089
swissprot - Q9Y2E5
swissprot - E9PCD7
swissprot - H0YA68
Ensembl - ENSG00000013288
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 man2b2ENSDARG00000079463Danio rerio
 MAN2B2ENSGALG00000015537Gallus gallus
 Man2b2ENSMUSG00000029119Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAN2B1 / O00754 / mannosidase alpha class 2B member 1ENSG0000010477428
MAN2A2 / P49641 / mannosidase alpha class 2A member 2ENSG0000019654725
MAN2A1 / Q16706 / mannosidase alpha class 2A member 1ENSG0000011289325
AC010422.5ENSG000002695906
AC010422.3ENSG000002692426


Protein motifs (from Interpro)
Interpro ID Name
 IPR000602  Glycoside hydrolase family 38, N-terminal domain
 IPR011013  Galactose mutarotase-like domain superfamily
 IPR011330  Glycoside hydrolase/deacetylase, beta/alpha-barrel
 IPR011682  Glycosyl hydrolase family 38, C-terminal
 IPR015341  Glycoside hydrolase family 38, central domain
 IPR027291  Glycoside hydrolase 38, N-terminal domain superfamily
 IPR028995  Glycoside hydrolase families 57/38, central domain superfamily
 IPR037094  Glycoside hydrolase family 38, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006013 mannose metabolic process IEA
 biological_processGO:0006517 protein deglycosylation IBA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009313 oligosaccharide catabolic process TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0043202 lysosomal lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004559 alpha-mannosidase activity IEA
 molecular_functionGO:0008496 mannan endo-1,6-alpha-mannosidase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Lysosomal oligosaccharide catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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