ENSMUSG00000029119


Mus musculus

Features
Gene ID: ENSMUSG00000029119
  
Biological name :Man2b2
  
Synonyms : Epididymis-specific alpha-mannosidase / Man2b2 / O54782
  
Possible biological names infered from orthology : mannosidase alpha class 2B member 2 / Q9Y2E5
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: B3
Gene start: 36806921
Gene end: 36830653
  
Corresponding Affymetrix probe sets: 10529584 (MoGene1.0st)   1416584_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031002
Ensembl peptide - ENSMUSP00000114319
Ensembl peptide - ENSMUSP00000115495
NCBI entrez gene - 17160     See in Manteia.
MGI - MGI:1195262
RefSeq - XM_006503767
RefSeq - NM_008550
RefSeq Peptide - NP_032576
swissprot - F6TMZ3
swissprot - O54782
swissprot - F6Z025
Ensembl - ENSMUSG00000029119
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAN2B2ENSG00000013288Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O09159 / Man2b1 / Lysosomal alpha-mannosidase / O00754* / AC010422.3* / AC010422.5* / mannosidase alpha class 2B member 1*ENSMUSG0000000514226
Man2a2 / Q8BRK9 / Alpha-mannosidase 2x / P49641* / mannosidase alpha class 2A member 2*ENSMUSG0000003888625
Man2a1 / P27046 / Alpha-mannosidase 2 / Q16706* / mannosidase alpha class 2A member 1*ENSMUSG0000002408523
Mrfap1 / Q9CQL7 / MORF4 family-associated protein 1 ENSMUSG000000553021


Protein motifs (from Interpro)
Interpro ID Name
 IPR000602  Glycoside hydrolase family 38, N-terminal domain
 IPR011013  Galactose mutarotase-like domain superfamily
 IPR011330  Glycoside hydrolase/deacetylase, beta/alpha-barrel
 IPR011682  Glycosyl hydrolase family 38, C-terminal
 IPR015341  Glycoside hydrolase family 38, central domain
 IPR027291  Glycoside hydrolase 38, N-terminal domain superfamily
 IPR028995  Glycoside hydrolase families 57/38, central domain superfamily
 IPR037094  Glycoside hydrolase family 38, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006013 mannose metabolic process IEA
 biological_processGO:0006517 protein deglycosylation IBA
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004559 alpha-mannosidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Lysosomal oligosaccharide catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000702 enlarged lymph nodes "lymph nodes of increased size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Lysttm1b(EUCOMM)Wtsi/Lysttm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Lysttm1b(EUCOMM)Wtsi/Tcp

 MP:0001102 small superior vagus ganglion "reduced size of the upper ganglion of the vagus nerve located at the jugular foramen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]
Show

Allelic Composition: Lysttm1b(EUCOMM)Wtsi/Lysttm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Lysttm1b(EUCOMM)Wtsi/Tcp

 MP:0002768 small adrenal glands "reduced size of endocrine glands located above the kidneys responsible for hormone and epinephrine secretion" [J:78062]
Show

Allelic Composition: Lysttm1b(EUCOMM)Wtsi/Lysttm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Lysttm1b(EUCOMM)Wtsi/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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