ENSG00000013441


Homo sapiens

Features
Gene ID: ENSG00000013441
  
Biological name :CLK1
  
Synonyms : CDC like kinase 1 / CLK1 / P49759
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q33.1
Gene start: 200853009
Gene end: 200864744
  
Corresponding Affymetrix probe sets: 214683_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000386875
Ensembl peptide - ENSP00000479484
Ensembl peptide - ENSP00000400487
Ensembl peptide - ENSP00000394734
Ensembl peptide - ENSP00000326830
Ensembl peptide - ENSP00000386358
NCBI entrez gene - 1195     See in Manteia.
OMIM - 601951
RefSeq - NM_004071
RefSeq - NM_001162407
RefSeq Peptide - NP_001155879
RefSeq Peptide - NP_004062
swissprot - P49759
swissprot - A0A087WVK0
swissprot - F8WBF5
swissprot - B8ZZR0
Ensembl - ENSG00000013441
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 clk4aENSDARG00000089372Danio rerio
 clk4bENSDARG00000005908Danio rerio
 CLK1ENSGALG00000028438Gallus gallus
 Clk1ENSMUSG00000026034Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLK4 / Q9HAZ1 / CDC like kinase 4ENSG0000011324072
CLK2 / P49760 / CDC like kinase 2ENSG0000017644451
CLK3 / P49761 / CDC like kinase 3ENSG0000017933549
PRPF4B / Q13523 / pre-mRNA processing factor 4BENSG0000011273928


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0043484 regulation of RNA splicing IMP
 biological_processGO:0046777 protein autophosphorylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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