ENSG00000176444


Homo sapiens

Features
Gene ID: ENSG00000176444
  
Biological name :CLK2
  
Synonyms : CDC like kinase 2 / CLK2 / P49760
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q22
Gene start: 155262868
Gene end: 155278491
  
Corresponding Affymetrix probe sets: 203229_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000354856
Ensembl peptide - ENSP00000357345
Ensembl peptide - ENSP00000347759
NCBI entrez gene - 1196     See in Manteia.
OMIM - 602989
RefSeq - XM_017000244
RefSeq - XM_005244878
RefSeq - XM_011509143
RefSeq - XM_011509147
RefSeq - XM_017000241
RefSeq - XM_017000242
RefSeq - XM_017000243
RefSeq - NM_001294338
RefSeq - NM_001294339
RefSeq - NM_003993
RefSeq Peptide - NP_003984
RefSeq Peptide - NP_001281267
RefSeq Peptide - NP_001281268
swissprot - B1AVT0
swissprot - P49760
swissprot - A8K7I0
Ensembl - ENSG00000176444
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 clk2aENSDARG00000062954Danio rerio
 clk2bENSDARG00000059870Danio rerio
 CLK2ENSGALG00000029444Gallus gallus
 Clk2ENSMUSG00000068917Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLK3 / P49761 / CDC like kinase 3ENSG0000017933560
CLK4 / Q9HAZ1 / CDC like kinase 4ENSG0000011324055
CLK1 / P49759 / CDC like kinase 1ENSG0000001344154
PRPF4B / Q13523 / pre-mRNA processing factor 4BENSG0000011273930


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0010033 response to organic substance IEA
 biological_processGO:0010212 response to ionizing radiation IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0043484 regulation of RNA splicing IDA
 biological_processGO:0045721 negative regulation of gluconeogenesis IEA
 biological_processGO:0046777 protein autophosphorylation ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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