ENSG00000013810


Homo sapiens

Features
Gene ID: ENSG00000013810
  
Biological name :TACC3
  
Synonyms : Q9Y6A5 / TACC3 / transforming acidic coiled-coil containing protein 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p16.3
Gene start: 1721490
Gene end: 1745176
  
Corresponding Affymetrix probe sets: 1569487_at (Human Genome U133 Plus 2.0 Array)   218308_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418727
Ensembl peptide - ENSP00000483196
Ensembl peptide - ENSP00000478580
Ensembl peptide - ENSP00000420838
Ensembl peptide - ENSP00000419210
Ensembl peptide - ENSP00000326550
Ensembl peptide - ENSP00000415914
Ensembl peptide - ENSP00000418095
NCBI entrez gene - 10460     See in Manteia.
OMIM - 605303
RefSeq - NM_006342
RefSeq - XM_017007653
RefSeq - XM_011513386
RefSeq - XM_005247930
RefSeq - XM_005247929
RefSeq Peptide - NP_006333
swissprot - E7EMT0
swissprot - Q8IX09
swissprot - Q9Y6A5
swissprot - H0Y8F2
swissprot - F8WC55
swissprot - C9JA91
swissprot - C9JWI7
Ensembl - ENSG00000013810
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tacc3ENSDARG00000005454Danio rerio
 TACC3ENSGALG00000015709Gallus gallus
 Tacc3ENSMUSG00000037313Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TACC2 / O95359 / transforming acidic coiled-coil containing protein 2ENSG0000013816228
TACC1 / O75410 / transforming acidic coiled-coil containing protein 1ENSG0000014752622


Protein motifs (from Interpro)
Interpro ID Name
 IPR007707  Transforming acidic coiled-coil-containing protein, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007091 metaphase/anaphase transition of mitotic cell cycle IMP
 biological_processGO:0008283 cell proliferation IBA
 biological_processGO:0021987 cerebral cortex development IBA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0060236 regulation of mitotic spindle organization IMP
 biological_processGO:1902850 microtubule cytoskeleton organization involved in mitosis IMP
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IBA
 cellular_componentGO:0072686 mitotic spindle IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
NOTCH3 Activation and Transmission of Signal to the Nucleus
Negative regulation of NOTCH4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000074181 NOTCH3 / Q9UM47  / reaction / complex
 ENSG00000204301 NOTCH4 / Q99466  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr