ENSG00000018189


Homo sapiens

Features
Gene ID: ENSG00000018189
  
Biological name :RUFY3
  
Synonyms : Q7L099 / RUFY3 / RUN and FYVE domain containing 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q13.3
Gene start: 70704204
Gene end: 70807315
  
Corresponding Affymetrix probe sets: 203724_s_at (Human Genome U133 Plus 2.0 Array)   210251_s_at (Human Genome U133 Plus 2.0 Array)   213430_at (Human Genome U133 Plus 2.0 Array)   213437_at (Human Genome U133 Plus 2.0 Array)   213939_s_at (Human Genome U133 Plus 2.0 Array)   227802_at (Human Genome U133 Plus 2.0 Array)   229334_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000421120
Ensembl peptide - ENSP00000420980
Ensembl peptide - ENSP00000425400
Ensembl peptide - ENSP00000426734
Ensembl peptide - ENSP00000426165
Ensembl peptide - ENSP00000425574
Ensembl peptide - ENSP00000226328
Ensembl peptide - ENSP00000370394
Ensembl peptide - ENSP00000399771
NCBI entrez gene - 22902     See in Manteia.
OMIM - 611194
RefSeq - XM_017007892
RefSeq - NM_014961
RefSeq - XM_005265656
RefSeq - XM_005265658
RefSeq - XM_011531750
RefSeq - XM_011531751
RefSeq - XM_011531752
RefSeq - XM_011531753
RefSeq - XM_011531754
RefSeq - XM_011531755
RefSeq - XM_011531756
RefSeq - XM_017007890
RefSeq - XM_017007891
RefSeq - NM_001037442
RefSeq - NM_001130709
RefSeq - NM_001291993
RefSeq - NM_001291994
RefSeq Peptide - NP_001124181
RefSeq Peptide - NP_001278922
RefSeq Peptide - NP_001278923
RefSeq Peptide - NP_055776
RefSeq Peptide - NP_001032519
swissprot - Q7L099
swissprot - A0A024RDD7
swissprot - D6RH24
swissprot - D6REM9
swissprot - D6RCQ1
swissprot - H0Y8G6
swissprot - H0Y8I0
Ensembl - ENSG00000018189
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rufy3ENSDARG00000029692Danio rerio
 RUFY3ENSGALG00000011564Gallus gallus
 Rufy3ENSMUSG00000029291Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RUFY2 / Q8WXA3 / RUN and FYVE domain containing 2ENSG0000020413051
RUFY1 / Q96T51 / RUN and FYVE domain containing 1ENSG0000017678350
Q96NL0 / RUNDC3B / RUN domain containing 3BENSG0000010578418
Q59EK9 / RUNDC3A / RUN domain containing 3AENSG0000010830917


Protein motifs (from Interpro)
Interpro ID Name
 IPR000306  FYVE zinc finger
 IPR004012  RUN domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR037213  RUN domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0045773 positive regulation of axon extension ISS
 biological_processGO:0050771 negative regulation of axonogenesis ISS
 biological_processGO:0090316 positive regulation of intracellular protein transport ISS
 biological_processGO:2000114 regulation of establishment of cell polarity ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030027 lamellipodium ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030175 filopodium ISS
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0030426 growth cone ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043204 perikaryon ISS
 cellular_componentGO:0071437 invadopodium IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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