ENSG00000023892


Homo sapiens

Features
Gene ID: ENSG00000023892
  
Biological name :DEF6
  
Synonyms : DEF6 / DEF6, guanine nucleotide exchange factor / Q9H4E7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.31
Gene start: 35297852
Gene end: 35321771
  
Corresponding Affymetrix probe sets: 221293_s_at (Human Genome U133 Plus 2.0 Array)   226659_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000319831
Ensembl peptide - ENSP00000415357
NCBI entrez gene - 50619     See in Manteia.
OMIM - 610094
RefSeq - NM_022047
RefSeq Peptide - NP_071330
swissprot - Q9H4E7
swissprot - H0Y7V7
Ensembl - ENSG00000023892
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 def6aENSDARG00000012247Danio rerio
 def6bENSDARG00000044524Danio rerio
 DEF6ENSGALG00000002615Gallus gallus
 Def6ENSMUSG00000002257Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UH65 / SWAP70 / switching B cell complex subunit SWAP70ENSG0000013378941


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011992  EF-hand domain pair
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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