ENSG00000133789


Homo sapiens

Features
Gene ID: ENSG00000133789
  
Biological name :SWAP70
  
Synonyms : Q9UH65 / SWAP70 / switching B cell complex subunit SWAP70
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p15.4
Gene start: 9664077
Gene end: 9752991
  
Corresponding Affymetrix probe sets: 209306_s_at (Human Genome U133 Plus 2.0 Array)   209307_at (Human Genome U133 Plus 2.0 Array)   210369_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000315630
Ensembl peptide - ENSP00000435587
Ensembl peptide - ENSP00000433824
Ensembl peptide - ENSP00000431768
Ensembl peptide - ENSP00000399056
NCBI entrez gene - 23075     See in Manteia.
OMIM - 604762
RefSeq - XM_005252830
RefSeq - NM_001297714
RefSeq - NM_015055
RefSeq Peptide - NP_001284643
RefSeq Peptide - NP_055870
swissprot - E9PJM7
swissprot - H0YDK5
swissprot - E9PJK8
swissprot - E7EMB1
swissprot - Q9UH65
Ensembl - ENSG00000133789
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 swap70aENSDARG00000051819Danio rerio
 swap70bENSDARG00000057286Danio rerio
 SWAP70ENSGALG00000005750Gallus gallus
 Q6A028ENSMUSG00000031015Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DEF6 / Q9H4E7 / DEF6, guanine nucleotide exchange factorENSG0000002389244


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0008064 regulation of actin polymerization or depolymerization IEA
 biological_processGO:0016444 somatic cell DNA recombination IEA
 biological_processGO:0030835 negative regulation of actin filament depolymerization IEA
 biological_processGO:0032233 positive regulation of actin filament bundle assembly IEA
 biological_processGO:0032880 regulation of protein localization IEA
 biological_processGO:0033633 negative regulation of cell-cell adhesion mediated by integrin IEA
 biological_processGO:0045190 isotype switching IEA
 biological_processGO:0051017 actin filament bundle assembly IEA
 biological_processGO:0060754 positive regulation of mast cell chemotaxis IEA
 biological_processGO:1902309 negative regulation of peptidyl-serine dephosphorylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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