ENSG00000033627


Homo sapiens

Features
Gene ID: ENSG00000033627
  
Biological name :ATP6V0A1
  
Synonyms : ATP6V0A1 / ATPase H+ transporting V0 subunit a1 / Q93050
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q21.2
Gene start: 42458844
Gene end: 42522611
  
Corresponding Affymetrix probe sets: 205095_s_at (Human Genome U133 Plus 2.0 Array)   212383_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468001
Ensembl peptide - ENSP00000467373
Ensembl peptide - ENSP00000468169
Ensembl peptide - ENSP00000468177
Ensembl peptide - ENSP00000264649
Ensembl peptide - ENSP00000342951
Ensembl peptide - ENSP00000377415
Ensembl peptide - ENSP00000443991
Ensembl peptide - ENSP00000446377
Ensembl peptide - ENSP00000466290
Ensembl peptide - ENSP00000466328
Ensembl peptide - ENSP00000466767
Ensembl peptide - ENSP00000466852
Ensembl peptide - ENSP00000466878
NCBI entrez gene - 535     See in Manteia.
OMIM - 192130
RefSeq - XM_017024774
RefSeq - NM_001130020
RefSeq - NM_001130021
RefSeq - NM_005177
RefSeq - XM_005257459
RefSeq - XM_005257461
RefSeq - XM_005257463
RefSeq - XM_011524908
RefSeq - XM_017024766
RefSeq - XM_017024767
RefSeq - XM_017024768
RefSeq - XM_017024769
RefSeq - XM_017024770
RefSeq - XM_017024771
RefSeq - XM_017024772
RefSeq - XM_017024773
RefSeq Peptide - NP_005168
RefSeq Peptide - NP_001123492
RefSeq Peptide - NP_001123493
swissprot - K7EM24
swissprot - K7EN36
swissprot - K7ENA1
swissprot - K7EPG4
swissprot - B7Z641
swissprot - K7ERA0
swissprot - K7ERA6
swissprot - Q93050
swissprot - B7Z2A9
swissprot - K7EQW2
swissprot - F5H1T6
swissprot - K7ELZ6
Ensembl - ENSG00000033627
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atp6v0a1aENSDARG00000020847Danio rerio
 atp6v0a1bENSDARG00000015174Danio rerio
 ATP6V0A1ENSGALG00000003256Gallus gallus
 Q9Z1G4ENSMUSG00000019302Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9HBG4 / ATP6V0A4 / ATPase H+ transporting V0 subunit a4ENSG0000010592961
Q9Y487 / ATP6V0A2 / ATPase H+ transporting V0 subunit a2ENSG0000018534454
Q13488 / TCIRG1 / T cell immune regulator 1, ATPase H+ transporting V0 subunit a3ENSG0000011071947


Protein motifs (from Interpro)
Interpro ID Name
 IPR002490  V-type ATPase, V0 complex, 116kDa subunit family
 IPR026028  ATPase, V0 complex, subunit 116kDa, eukaryotic


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007035 vacuolar acidification TAS
 biological_processGO:0008286 insulin receptor signaling pathway TAS
 biological_processGO:0015986 ATP synthesis coupled proton transport IBA
 biological_processGO:0015991 ATP hydrolysis coupled proton transport IEA
 biological_processGO:0016241 regulation of macroautophagy IMP
 biological_processGO:0033572 transferrin transport TAS
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0070072 vacuolar proton-transporting V-type ATPase complex assembly IBA
 biological_processGO:0090383 phagosome acidification TAS
 biological_processGO:1901998 toxin transport IEA
 cellular_componentGO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005765 lysosomal membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016471 vacuolar proton-transporting V-type ATPase complex IBA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0030667 secretory granule membrane TAS
 cellular_componentGO:0030670 phagocytic vesicle membrane TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0033179 proton-transporting V-type ATPase, V0 domain IEA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015078 proton transmembrane transporter activity IEA
 molecular_functionGO:0046961 proton-transporting ATPase activity, rotational mechanism IBA
 molecular_functionGO:0051117 ATPase binding IPI


Pathways (from Reactome)
Pathway description
ROS, RNS production in phagocytes
Neutrophil degranulation
Insulin receptor recycling
Transferrin endocytosis and recycling
Ion channel transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000110719 Q13488 / TCIRG1 / T cell immune regulator 1, ATPase H+ transporting V0 subunit a3  / complex
 ENSG00000105929 Q9HBG4 / ATP6V0A4 / ATPase H+ transporting V0 subunit a4  / complex
 ENSG00000185344 Q9Y487 / ATP6V0A2 / ATPase H+ transporting V0 subunit a2  / complex






 

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contact: otassy@igbmc.fr