ENSG00000035499


Homo sapiens

Features
Gene ID: ENSG00000035499
  
Biological name :DEPDC1B
  
Synonyms : DEPDC1B / DEP domain containing 1B / Q8WUY9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q12.1
Gene start: 60596912
Gene end: 60700190
  
Corresponding Affymetrix probe sets: 226980_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000426979
Ensembl peptide - ENSP00000427527
Ensembl peptide - ENSP00000265036
Ensembl peptide - ENSP00000389101
NCBI entrez gene - 55789     See in Manteia.
OMIM - 616073
RefSeq - XM_017009629
RefSeq - NM_001145208
RefSeq - NM_018369
RefSeq - XM_011543509
RefSeq - XM_011543510
RefSeq Peptide - NP_060839
RefSeq Peptide - NP_001138680
swissprot - D6RIB0
swissprot - Q8WUY9
swissprot - D6RDV9
Ensembl - ENSG00000035499
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DEPDC1BENSGALG00000014729Gallus gallus
 Q8BH88ENSMUSG00000021697Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DEPDC1 / Q5TB30 / DEP domain containing 1ENSG0000002452654
DEPDC7 / Q96QD5 / DEP domain containing 7ENSG0000012169022
DEPDC4 / Q8N2C3 / DEP domain containing 4ENSG000001661539


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR000591  DEP domain
 IPR008936  Rho GTPase activation protein
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IMP
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005096 GTPase activator activity TAS


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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