ENSG00000024526


Homo sapiens

Features
Gene ID: ENSG00000024526
  
Biological name :DEPDC1
  
Synonyms : DEPDC1 / DEP domain containing 1 / Q5TB30
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p31.3
Gene start: 68474152
Gene end: 68497221
  
Corresponding Affymetrix probe sets: 220295_x_at (Human Genome U133 Plus 2.0 Array)   222958_s_at (Human Genome U133 Plus 2.0 Array)   232278_s_at (Human Genome U133 Plus 2.0 Array)   235545_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000412292
Ensembl peptide - ENSP00000436464
Ensembl peptide - ENSP00000431477
Ensembl peptide - ENSP00000360005
NCBI entrez gene - 55635     See in Manteia.
OMIM - 612002
RefSeq - NM_001114120
RefSeq - NM_017779
RefSeq Peptide - NP_001107592
RefSeq Peptide - NP_060249
swissprot - Q5TB30
swissprot - H0YES2
swissprot - E9PL61
Ensembl - ENSG00000024526
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 depdc1aENSDARG00000018165Danio rerio
 DEPDC1ENSGALG00000011275Gallus gallus
 Q8CIG0ENSMUSG00000028175Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8WUY9 / DEPDC1B / DEP domain containing 1BENSG0000003549935
DEPDC7 / Q96QD5 / DEP domain containing 7ENSG0000012169012
DEPDC4 / Q8N2C3 / DEP domain containing 4ENSG000001661536


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR000591  DEP domain
 IPR008936  Rho GTPase activation protein
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0017053 transcriptional repressor complex IDA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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