ENSG00000121690


Homo sapiens

Features
Gene ID: ENSG00000121690
  
Biological name :DEPDC7
  
Synonyms : DEPDC7 / DEP domain containing 7 / Q96QD5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p13
Gene start: 33015864
Gene end: 33033582
  
Corresponding Affymetrix probe sets: 228293_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000241051
Ensembl peptide - ENSP00000308971
NCBI entrez gene - 91614     See in Manteia.
OMIM - 612294
RefSeq - NM_001077242
RefSeq - NM_139160
RefSeq Peptide - NP_001070710
RefSeq Peptide - NP_631899
swissprot - Q96QD5
Ensembl - ENSG00000121690
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 depdc7ENSDARG00000055043Danio rerio
 si:ch211-11i22.4ENSDARG00000053246Danio rerio
 DEPDC7ENSGALG00000011681Gallus gallus
 Depdc7ENSMUSG00000027173Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8WUY9 / DEPDC1B / DEP domain containing 1BENSG0000003549923
DEPDC1 / Q5TB30 / DEP domain containing 1ENSG0000002452619
DEPDC4 / Q8N2C3 / DEP domain containing 4ENSG0000016615317


Protein motifs (from Interpro)
Interpro ID Name
 IPR000591  DEP domain
 IPR008936  Rho GTPase activation protein
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005096 GTPase activator activity TAS


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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