ENSG00000038274


Homo sapiens

Features
Gene ID: ENSG00000038274
  
Biological name :MAT2B
  
Synonyms : MAT2B / methionine adenosyltransferase 2B / Q9NZL9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q34
Gene start: 163503114
Gene end: 163519336
  
Corresponding Affymetrix probe sets: 217993_s_at (Human Genome U133 Plus 2.0 Array)   229284_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000325425
Ensembl peptide - ENSP00000431071
Ensembl peptide - ENSP00000428046
Ensembl peptide - ENSP00000397371
Ensembl peptide - ENSP00000280969
NCBI entrez gene - 27430     See in Manteia.
OMIM - 605527
RefSeq - NM_182796
RefSeq - NM_013283
RefSeq Peptide - NP_037415
RefSeq Peptide - NP_877725
swissprot - Q9NZL9
swissprot - A0A140VJP2
swissprot - H7C0X7
swissprot - E5RJR3
Ensembl - ENSG00000038274
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mat2bENSDARG00000012932Danio rerio
 MAT2BENSGALG00000001750Gallus gallus
 Mat2bENSMUSG00000042032Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005913  dTDP-4-dehydrorhamnose reductase family
 IPR029903  RmlD-like substrate binding domain
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006556 S-adenosylmethionine biosynthetic process IEA
 biological_processGO:0006730 one-carbon metabolic process IEA
 biological_processGO:0032259 methylation TAS
 biological_processGO:0050790 regulation of catalytic activity IEA
 cellular_componentGO:0005622 intracellular IC
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0048269 methionine adenosyltransferase complex IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0048270 methionine adenosyltransferase regulator activity IDA


Pathways (from Reactome)
Pathway description
Methylation
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000168906 MAT2A / P31153 / methionine adenosyltransferase 2A  / complex






 

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