ENSG00000168906


Homo sapiens

Features
Gene ID: ENSG00000168906
  
Biological name :MAT2A
  
Synonyms : MAT2A / methionine adenosyltransferase 2A / P31153
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p11.2
Gene start: 85539165
Gene end: 85545280
  
Corresponding Affymetrix probe sets: 200768_s_at (Human Genome U133 Plus 2.0 Array)   200769_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000303147
Ensembl peptide - ENSP00000386353
NCBI entrez gene - 4144     See in Manteia.
OMIM - 601468
RefSeq - NM_005911
RefSeq Peptide - NP_005902
swissprot - A0A140VJP5
swissprot - P31153
Ensembl - ENSG00000168906
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mat2aaENSDARG00000040334Danio rerio
 mat2abENSDARG00000037121Danio rerio
 Mat2aENSMUSG00000053907Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAT1A / Q00266 / methionine adenosyltransferase 1AENSG0000015122484


Protein motifs (from Interpro)
Interpro ID Name
 IPR002133  S-adenosylmethionine synthetase
 IPR022628  S-adenosylmethionine synthetase, N-terminal
 IPR022629  S-adenosylmethionine synthetase, central domain
 IPR022630  S-adenosylmethionine synthetase, C-terminal
 IPR022631  S-adenosylmethionine synthetase, conserved site
 IPR022636  S-adenosylmethionine synthetase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006556 S-adenosylmethionine biosynthetic process IDA
 biological_processGO:0006730 one-carbon metabolic process IEA
 biological_processGO:0032259 methylation TAS
 biological_processGO:0034214 protein hexamerization IDA
 biological_processGO:0051291 protein heterooligomerization IDA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0048269 methionine adenosyltransferase complex IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004478 methionine adenosyltransferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Methylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000038274 MAT2B / Q9NZL9 / methionine adenosyltransferase 2B  / complex






 

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