ENSG00000038358


Homo sapiens

Features
Gene ID: ENSG00000038358
  
Biological name :EDC4
  
Synonyms : EDC4 / enhancer of mRNA decapping 4 / Q6P2E9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q22.1
Gene start: 67873023
Gene end: 67884503
  
Corresponding Affymetrix probe sets: 202496_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000351811
Ensembl peptide - ENSP00000459624
Ensembl peptide - ENSP00000460563
Ensembl peptide - ENSP00000458357
NCBI entrez gene - 23644     See in Manteia.
OMIM - 606030
RefSeq - NM_014329
RefSeq Peptide - NP_055144
swissprot - Q6P2E9
swissprot - I3L0V0
swissprot - I3L2F4
swissprot - I3L3M2
Ensembl - ENSG00000038358
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 edc4ENSDARG00000062266Danio rerio
 EDC4ENSGALG00000040875Gallus gallus
 Edc4ENSMUSG00000036270Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR032401  Enhancer of mRNA-decapping protein 4, WD40 repeat region
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA IBA
 biological_processGO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay TAS
 cellular_componentGO:0000932 P-body IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
mRNA decay by 5 to 3 exoribonuclease


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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