ENSG00000047648


Homo sapiens

Features
Gene ID: ENSG00000047648
  
Biological name :ARHGAP6
  
Synonyms : ARHGAP6 / O43182 / Rho GTPase activating protein 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: p22.2
Gene start: 11137543
Gene end: 11665701
  
Corresponding Affymetrix probe sets: 206167_s_at (Human Genome U133 Plus 2.0 Array)   208085_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000435767
Ensembl peptide - ENSP00000370094
Ensembl peptide - ENSP00000370112
Ensembl peptide - ENSP00000302312
Ensembl peptide - ENSP00000338967
Ensembl peptide - ENSP00000370093
NCBI entrez gene - 395     See in Manteia.
OMIM - 300118
RefSeq - NM_001287242
RefSeq - NM_006125
RefSeq - NM_013423
RefSeq - NM_013427
RefSeq Peptide - NP_001274171
RefSeq Peptide - NP_006116
RefSeq Peptide - NP_038267
RefSeq Peptide - NP_038286
swissprot - O43182
swissprot - H7BYE6
Ensembl - ENSG00000047648
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARHGAP6ENSGALG00000016602Gallus gallus
 O54834ENSMUSG00000031355Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6ZRI8 / ARHGAP36 / Rho GTPase activating protein 36ENSG0000014725620
Q6P4F7 / ARHGAP11A / Rho GTPase activating protein 11AENSG0000019882614
Q9Y3M8 / STARD13 / StAR related lipid transfer domain containing 13ENSG0000013312114
Q92502 / STARD8 / StAR related lipid transfer domain containing 8ENSG0000013005213
DLC1 / Q96QB1 / DLC1 Rho GTPase activating proteinENSG0000016474113
Q8N392 / ARHGAP18 / Rho GTPase activating protein 18ENSG0000014637612
Q5TG30 / ARHGAP40 / Rho GTPase activating protein 40ENSG0000012414311
Q9P2N2 / ARHGAP28 / Rho GTPase activating protein 28ENSG0000008875610
Q3KRB8 / AC091057.5 / Rho GTPase-activating protein 11B ENSG000002849067
Q3KRB8 / ARHGAP11B / Rho GTPase activating protein 11BENSG000002850777


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR008936  Rho GTPase activation protein
 IPR030772  Rho GTPase-activating protein 6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007266 Rho protein signal transduction NAS
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0030041 actin filament polymerization NAS
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0048041 focal adhesion assembly IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 biological_processGO:0051497 negative regulation of stress fiber assembly IMP
 biological_processGO:0051895 negative regulation of focal adhesion assembly IMP
 cellular_componentGO:0005737 cytoplasm IMP
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005884 actin filament NAS
 cellular_componentGO:0015629 actin cytoskeleton ISS
 molecular_functionGO:0005070 SH3/SH2 adaptor activity TAS
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0017124 SH3 domain binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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