ENSG00000088756


Homo sapiens

Features
Gene ID: ENSG00000088756
  
Biological name :ARHGAP28
  
Synonyms : ARHGAP28 / Q9P2N2 / Rho GTPase activating protein 28
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: p11.31
Gene start: 6729718
Gene end: 6915716
  
Corresponding Affymetrix probe sets: 220381_at (Human Genome U133 Plus 2.0 Array)   220382_s_at (Human Genome U133 Plus 2.0 Array)   227911_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463143
Ensembl peptide - ENSP00000463672
Ensembl peptide - ENSP00000464310
Ensembl peptide - ENSP00000464141
Ensembl peptide - ENSP00000262227
Ensembl peptide - ENSP00000313506
Ensembl peptide - ENSP00000372964
Ensembl peptide - ENSP00000392660
Ensembl peptide - ENSP00000433390
Ensembl peptide - ENSP00000435990
Ensembl peptide - ENSP00000437262
Ensembl peptide - ENSP00000462831
Ensembl peptide - ENSP00000462912
NCBI entrez gene - 79822     See in Manteia.
OMIM - 610592
RefSeq - NM_001010000
RefSeq - XM_005258144
RefSeq - XM_005258145
RefSeq - XM_005258146
RefSeq Peptide - NP_001010000
swissprot - J3QLR3
swissprot - E9PMX7
swissprot - Q9P2N2
swissprot - J3QRC2
swissprot - E9PL26
swissprot - J3KT69
swissprot - J3KTC0
swissprot - J3QKM0
Ensembl - ENSG00000088756
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap28ENSDARG00000101350Danio rerio
 ARHGAP28ENSGALG00000014758Gallus gallus
 Q8BN58ENSMUSG00000024043Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8N392 / ARHGAP18 / Rho GTPase activating protein 18ENSG0000014637637
Q5TG30 / ARHGAP40 / Rho GTPase activating protein 40ENSG0000012414334
Q9Y3M8 / STARD13 / StAR related lipid transfer domain containing 13ENSG0000013312119
Q92502 / STARD8 / StAR related lipid transfer domain containing 8ENSG0000013005219
DLC1 / Q96QB1 / DLC1 Rho GTPase activating proteinENSG0000016474118
O43182 / ARHGAP6 / Rho GTPase activating protein 6ENSG0000004764817
Q6ZRI8 / ARHGAP36 / Rho GTPase activating protein 36ENSG0000014725614
Q6P4F7 / ARHGAP11A / Rho GTPase activating protein 11AENSG0000019882614
Q3KRB8 / ARHGAP11B / Rho GTPase activating protein 11BENSG000002850778
Q3KRB8 / AC091057.5 / Rho GTPase-activating protein 11B ENSG000002849068


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR008936  Rho GTPase activation protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 biological_processGO:0051497 negative regulation of stress fiber assembly IEA
 biological_processGO:1904425 negative regulation of GTP binding IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005096 GTPase activator activity TAS


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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