ENSMUSG00000024043


Mus musculus

Features
Gene ID: ENSMUSG00000024043
  
Biological name :Arhgap28
  
Synonyms : Arhgap28 / Mus musculus Rho GTPase activating protein 28 (Arhgap28), transcript variant 2, mRNA. / Q8BN58
  
Possible biological names infered from orthology : Q9P2N2 / Rho GTPase activating protein 28
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: E1.2
Gene start: 67842713
Gene end: 68004120
  
Corresponding Affymetrix probe sets: 10452613 (MoGene1.0st)   1434809_at (Mouse Genome 430 2.0 Array)   1438139_at (Mouse Genome 430 2.0 Array)   1458688_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000128194
Ensembl peptide - ENSMUSP00000131903
Ensembl peptide - ENSMUSP00000132087
Ensembl peptide - ENSMUSP00000024840
Ensembl peptide - ENSMUSP00000130960
NCBI entrez gene - 268970     See in Manteia.
MGI - MGI:2147003
RefSeq - XM_017317489
RefSeq - NM_001347410
RefSeq - NM_172964
RefSeq - XM_006524341
RefSeq - XM_006524342
RefSeq - XM_006524343
RefSeq - XM_017317488
RefSeq Peptide - NP_001334339
RefSeq Peptide - NP_766552
swissprot - F6ZDY5
swissprot - F6XG99
swissprot - Q8BN58
swissprot - E9Q642
Ensembl - ENSMUSG00000024043
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap28ENSDARG00000101350Danio rerio
 ARHGAP28ENSGALG00000014758Gallus gallus
 Q9P2N2ENSG00000088756Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8K0Q5 / Arhgap18 / Rho GTPase-activating protein 18 / Q8N392*ENSMUSG0000003903138
E9Q6X9 / Arhgap40 / Rho GTPase-activating protein 40 / Q5TG30*ENSMUSG0000007462532
Q923Q2 / Stard13 / StAR-related lipid transfer protein 13 / Q9Y3M8* / StAR related lipid transfer domain containing 13*ENSMUSG0000001612817
Dlc1 / DLC1 Rho GTPase activating protein / Q96QB1*ENSMUSG0000003152316
O54834 / Arhgap6 / Rho GTPase activating protein 6 / O43182*ENSMUSG0000003135516
Q8K031 / Stard8 / StAR-related lipid transfer protein 8 / Q92502* / StAR related lipid transfer domain containing 8*ENSMUSG0000003121615
B1AUC7 / Arhgap36 / Mus musculus Rho GTPase activating protein 36 (Arhgap36), transcript variant 2, mRNA. / Q6ZRI8* / Rho GTPase activating protein 36*ENSMUSG0000003619812
Q80Y19 / Arhgap11a / Rho GTPase-activating protein 11A / Q6P4F7*ENSMUSG0000004121911
Gm42906ENSMUSG000001070111


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR008936  Rho GTPase activation protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051497 negative regulation of stress fiber assembly IDA
 biological_processGO:1904425 negative regulation of GTP binding IDA
 molecular_functionGO:0005096 GTPase activator activity ISS


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lrrk2tm1.1Hlme/Lrrk2+
Genetic Background: involves: C57BL/6 * C57BL/6J

Allelic Composition: Arhgap28tm2b(KOMP)Wtsi/Arhgap28tm2b(KOMP)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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