ENSG00000146376


Homo sapiens

Features
Gene ID: ENSG00000146376
  
Biological name :ARHGAP18
  
Synonyms : ARHGAP18 / Q8N392 / Rho GTPase activating protein 18
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q22.33
Gene start: 129576132
Gene end: 129710225
  
Corresponding Affymetrix probe sets: 225166_at (Human Genome U133 Plus 2.0 Array)   225171_at (Human Genome U133 Plus 2.0 Array)   225173_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357131
NCBI entrez gene - 93663     See in Manteia.
OMIM - 613351
RefSeq - XM_017011494
RefSeq - NM_033515
RefSeq - XM_005267212
RefSeq - XM_005267213
RefSeq Peptide - NP_277050
swissprot - Q8N392
Ensembl - ENSG00000146376
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap18ENSDARG00000074740Danio rerio
 ARHGAP18ENSGALG00000031843Gallus gallus
 Q8K0Q5ENSMUSG00000039031Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5TG30 / ARHGAP40 / Rho GTPase activating protein 40ENSG0000012414336
Q9P2N2 / ARHGAP28 / Rho GTPase activating protein 28ENSG0000008875632
Q9Y3M8 / STARD13 / StAR related lipid transfer domain containing 13ENSG0000013312122
DLC1 / Q96QB1 / DLC1 Rho GTPase activating proteinENSG0000016474122
Q92502 / STARD8 / StAR related lipid transfer domain containing 8ENSG0000013005219
O43182 / ARHGAP6 / Rho GTPase activating protein 6ENSG0000004764817
Q6P4F7 / ARHGAP11A / Rho GTPase activating protein 11AENSG0000019882615
Q6ZRI8 / ARHGAP36 / Rho GTPase activating protein 36ENSG0000014725614
Q3KRB8 / ARHGAP11B / Rho GTPase activating protein 11BENSG0000028507710
Q3KRB8 / AC091057.5 / Rho GTPase-activating protein 11B ENSG0000028490610


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR008936  Rho GTPase activation protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IMP
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0030833 regulation of actin filament polymerization IMP
 biological_processGO:0032956 regulation of actin cytoskeleton organization IMP
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IMP
 biological_processGO:2000145 regulation of cell motility IMP
 cellular_componentGO:0005737 cytoplasm IMP
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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