ENSDARG00000074740


Danio rerio

Features
Gene ID: ENSDARG00000074740
  
Biological name :arhgap18
  
Synonyms : arhgap18 / Rho GTPase activating protein 18
  
Possible biological names infered from orthology : Q8K0Q5 / Q8N392
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 2064400
Gene end: 2090789
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000100615
swissprot - E7F5Q5
ZFIN ID - ZDB-GENE-070502-1
Ensembl - ENSDARG00000074740
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARHGAP18ENSGALG00000031843Gallus gallus
 Q8N392ENSG00000146376Homo sapiens
 Q8K0Q5ENSMUSG00000039031Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
stard13b / StAR-related lipid transfer (START) domain containing 13b / Q9Y3M8* / Q923Q2* / STARD13* / StAR-related lipid transfer protein 13 * / StAR related lipid transfer domain containing 13*ENSDARG0000009895418
arhgap28 / Rho GTPase activating protein 28 / Q9P2N2*ENSDARG0000010135018
dlc1 / DLC1 Rho GTPase activating protein / Q96QB1*ENSDARG0000007931718
si:dkeyp-23e4.3ENSDARG0000007481917
arhgap36 / Rho GTPase activating protein 36ENSDARG0000005967216
stard8 / StAR-related lipid transfer (START) domain containing 8 / Q92502* / Q8K031* / StAR-related lipid transfer protein 8 * / StAR related lipid transfer domain containing 8*ENSDARG0000001400316
stard13a / StAR-related lipid transfer (START) domain containing 13a / Q9Y3M8* / Q923Q2* / STARD13* / StAR-related lipid transfer protein 13 * / StAR related lipid transfer domain containing 13*ENSDARG0000007954216
arhgap11a / Rho GTPase activating protein 11A / Q3KRB8* / Q6P4F7* / Q80Y19* / ARHGAP11B* / AC091057.5* / Rho GTPase activating protein 11B*ENSDARG0000010001913
zgc:153345ENSDARG0000005562212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR008936  Rho GTPase activation protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:1903671 negative regulation of sprouting angiogenesis IMP


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000014 dorsal aorta dorsal aorta decreased diameter , abnormal
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 ZFA:0000029 hindbrain hindbrain edematous , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000084 yolk yolk edematous , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel increased length , abnormal
intersegmental vessel has extra parts of type endothelial cell filopodium, abnormal
intersegmental vessel sprouting angiogenesis increased process quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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