ENSG00000050438


Homo sapiens

Features
Gene ID: ENSG00000050438
  
Biological name :SLC4A8
  
Synonyms : Q2Y0W8 / SLC4A8 / solute carrier family 4 member 8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.13
Gene start: 51391317
Gene end: 51515763
  
Corresponding Affymetrix probe sets: 1554113_a_at (Human Genome U133 Plus 2.0 Array)   207056_s_at (Human Genome U133 Plus 2.0 Array)   228175_at (Human Genome U133 Plus 2.0 Array)   228935_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000351483
Ensembl peptide - ENSP00000405812
Ensembl peptide - ENSP00000441520
Ensembl peptide - ENSP00000442561
NCBI entrez gene - 9498     See in Manteia.
OMIM - 605024
RefSeq - XM_017020242
RefSeq - NM_001039960
RefSeq - NM_001258401
RefSeq - NM_001258402
RefSeq - NM_001258403
RefSeq - NM_001267615
RefSeq - XM_006719700
RefSeq - XM_011539010
RefSeq - XM_011539011
RefSeq - XM_017020240
RefSeq - XM_017020241
RefSeq Peptide - NP_001035049
RefSeq Peptide - NP_001245330
RefSeq Peptide - NP_001245331
RefSeq Peptide - NP_001245332
RefSeq Peptide - NP_001254544
swissprot - Q2Y0W8
Ensembl - ENSG00000050438
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc4a8ENSDARG00000015531Danio rerio
 SLC4A8ENSGALG00000031274Gallus gallus
 Q8JZR6ENSMUSG00000023032Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6U841 / SLC4A10 / solute carrier family 4 member 10ENSG0000014429077
Q9Y6M7 / SLC4A7 / solute carrier family 4 member 7ENSG0000003386773
Q9Y6R1 / SLC4A4 / solute carrier family 4 member 4ENSG0000008049351
Q9BY07 / SLC4A5 / solute carrier family 4 member 5ENSG0000018868746
Q96Q91 / SLC4A9 / solute carrier family 4 member 9ENSG0000011307340
P48751 / SLC4A3 / solute carrier family 4 member 3ENSG0000011492335
P04920 / SLC4A2 / solute carrier family 4 member 2ENSG0000016488935
P02730 / SLC4A1 / solute carrier family 4 member 1 (Diego blood group)ENSG0000000493930
Q8NBS3 / SLC4A11 / solute carrier family 4 member 11ENSG0000008883619


Protein motifs (from Interpro)
Interpro ID Name
 IPR003020  Bicarbonate transporter, eukaryotic
 IPR003024  Sodium bicarbonate cotransporter
 IPR011531  Bicarbonate transporter, C-terminal
 IPR013769  Band 3 cytoplasmic domain
 IPR016152  Phosphotransferase/anion transporter


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006820 anion transport IEA
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0015701 bicarbonate transport TAS
 biological_processGO:0051453 regulation of intracellular pH IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0098656 anion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032809 neuronal cell body membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 molecular_functionGO:0005452 inorganic anion exchanger activity TAS
 molecular_functionGO:0008509 anion transmembrane transporter activity IEA
 molecular_functionGO:0008510 sodium:bicarbonate symporter activity IBA
 molecular_functionGO:0015297 antiporter activity IEA
 molecular_functionGO:0015301 anion:anion antiporter activity IEA


Pathways (from Reactome)
Pathway description
Bicarbonate transporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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