ENSG00000051108


Homo sapiens

Features
Gene ID: ENSG00000051108
  
Biological name :HERPUD1
  
Synonyms : HERPUD1 / homocysteine inducible ER protein with ubiquitin like domain 1 / Q15011
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q13
Gene start: 56932048
Gene end: 56944863
  
Corresponding Affymetrix probe sets: 1569380_a_at (Human Genome U133 Plus 2.0 Array)   217168_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000455094
Ensembl peptide - ENSP00000456384
Ensembl peptide - ENSP00000457095
Ensembl peptide - ENSP00000457321
Ensembl peptide - ENSP00000457955
Ensembl peptide - ENSP00000300302
Ensembl peptide - ENSP00000340931
Ensembl peptide - ENSP00000369118
Ensembl peptide - ENSP00000409555
Ensembl peptide - ENSP00000455841
NCBI entrez gene - 9709     See in Manteia.
OMIM - 608070
RefSeq - NM_001272103
RefSeq - NM_014685
RefSeq - NM_001010989
RefSeq Peptide - NP_001259032
RefSeq Peptide - NP_001010989
RefSeq Peptide - NP_055500
swissprot - Q15011
swissprot - H3BP08
swissprot - H3BQM2
swissprot - H3BRS4
swissprot - H3BTA8
swissprot - H3BTT7
swissprot - H3BV54
Ensembl - ENSG00000051108
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 herpud1ENSDARG00000024314Danio rerio
 HERPUD1ENSGALG00000001220Gallus gallus
 Q9JJK5ENSMUSG00000031770Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BSE4 / HERPUD2 / HERPUD family member 2ENSG0000012255738


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0006986 response to unfolded protein IEP
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IEA
 biological_processGO:0030970 retrograde protein transport, ER to cytosol IMP
 biological_processGO:0031396 regulation of protein ubiquitination IEA
 biological_processGO:0032092 positive regulation of protein binding IEA
 biological_processGO:0032469 endoplasmic reticulum calcium ion homeostasis IDA
 biological_processGO:0034976 response to endoplasmic reticulum stress TAS
 biological_processGO:0036499 PERK-mediated unfolded protein response TAS
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IDA
 biological_processGO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process IMP
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IGI
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034704 calcium channel complex IPI
 cellular_componentGO:1990037 Lewy body core IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0044325 ion channel binding IPI


Pathways (from Reactome)
Pathway description
ATF4 activates genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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