ENSG00000055957


Homo sapiens

Features
Gene ID: ENSG00000055957
  
Biological name :ITIH1
  
Synonyms : inter-alpha-trypsin inhibitor heavy chain 1 / ITIH1 / P19827
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p21.1
Gene start: 52777592
Gene end: 52792068
  
Corresponding Affymetrix probe sets: 210888_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443847
Ensembl peptide - ENSP00000384589
Ensembl peptide - ENSP00000273283
Ensembl peptide - ENSP00000417340
Ensembl peptide - ENSP00000419957
Ensembl peptide - ENSP00000395836
NCBI entrez gene - 3697     See in Manteia.
OMIM - 147270
RefSeq - NM_002215
RefSeq - NM_001166434
RefSeq - NM_001166435
RefSeq - NM_001166436
RefSeq Peptide - NP_001159906
RefSeq Peptide - NP_002206
RefSeq Peptide - NP_001159908
RefSeq Peptide - NP_001159907
swissprot - P19827
swissprot - B5MCP1
swissprot - F8WAS2
swissprot - H7C0N0
swissprot - H7C5I0
Ensembl - ENSG00000055957
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itih1ENSDARG00000055053Danio rerio
 itih3aENSDARG00000055036Danio rerio
 ENSGALG00000001697Gallus gallus
 Itih1ENSMUSG00000006529Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITIH3 / Q06033 / inter-alpha-trypsin inhibitor heavy chain 3ENSG0000016226754
ITIH2 / P19823 / inter-alpha-trypsin inhibitor heavy chain 2ENSG0000015165538
ITIH4 / Q14624 / inter-alpha-trypsin inhibitor heavy chain family member 4ENSG0000005595534
ITIH6 / Q6UXX5 / inter-alpha-trypsin inhibitor heavy chain family member 6ENSG0000010231331
ITIH5 / inter-alpha-trypsin inhibitor heavy chain family member 5ENSG0000012324325


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR010600  Inter-alpha-trypsin inhibitor heavy chain, C-terminal
 IPR013694  VIT domain
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0030212 hyaluronan metabolic process IEA
 cellular_componentGO:0005576 extracellular region NAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0072562 blood microparticle HDA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0005509 calcium ion binding TAS
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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