ENSG00000062485


Homo sapiens

Features
Gene ID: ENSG00000062485
  
Biological name :CS
  
Synonyms : citrate synthase / CS / O75390
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.3
Gene start: 56271699
Gene end: 56300392
  
Corresponding Affymetrix probe sets: 208660_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000447948
Ensembl peptide - ENSP00000342056
Ensembl peptide - ENSP00000440543
Ensembl peptide - ENSP00000446492
Ensembl peptide - ENSP00000446779
Ensembl peptide - ENSP00000447346
Ensembl peptide - ENSP00000447442
Ensembl peptide - ENSP00000447582
Ensembl peptide - ENSP00000447986
Ensembl peptide - ENSP00000448166
Ensembl peptide - ENSP00000448172
Ensembl peptide - ENSP00000448409
Ensembl peptide - ENSP00000448667
Ensembl peptide - ENSP00000449025
Ensembl peptide - ENSP00000449080
Ensembl peptide - ENSP00000449427
Ensembl peptide - ENSP00000449491
Ensembl peptide - ENSP00000449571
Ensembl peptide - ENSP00000449753
Ensembl peptide - ENSP00000450101
Ensembl peptide - ENSP00000450312
Ensembl peptide - ENSP00000450403
NCBI entrez gene - 1431     See in Manteia.
OMIM - 118950
RefSeq - NM_004077
RefSeq Peptide - NP_004068
swissprot - A0A0C4DGI3
swissprot - B4DJV2
swissprot - F8VPA1
swissprot - F8VPF9
swissprot - F8VR34
swissprot - F8VRI6
swissprot - F8VRP1
swissprot - F8VTT8
swissprot - F8VU34
swissprot - F8VVY4
swissprot - F8VWQ5
swissprot - F8VX07
swissprot - F8VX68
swissprot - F8VZK9
swissprot - F8W0J2
swissprot - F8W1S4
swissprot - F8W4S1
swissprot - H0YH82
swissprot - F8W642
swissprot - H0YIC4
swissprot - O75390
swissprot - A0A024RB75
Ensembl - ENSG00000062485
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 csENSDARG00000103364Danio rerio
 CSENSGALG00000030466Gallus gallus
 CsENSMUSG00000005683Mus musculus
 CslENSMUSG00000046934Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002020  Citrate synthase
 IPR010109  Citrate synthase, eukaryotic-type
 IPR016142  Citrate synthase-like, large alpha subdomain
 IPR016143  Citrate synthase-like, small alpha subdomain
 IPR019810  Citrate synthase active site
 IPR036969  Citrate synthase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IDA
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0006101 citrate metabolic process IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004108 citrate (Si)-synthase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer IEA


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Citric acid cycle (TCA cycle)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000062485 CS / O75390 / citrate synthase  / complex






 

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contact: otassy@igbmc.fr