ENSG00000066294


Homo sapiens

Features
Gene ID: ENSG00000066294
  
Biological name :CD84
  
Synonyms : CD84 / CD84 molecule / Q9UIB8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q23.3
Gene start: 160541095
Gene end: 160579516
  
Corresponding Affymetrix probe sets: 205988_at (Human Genome U133 Plus 2.0 Array)   211188_at (Human Genome U133 Plus 2.0 Array)   211189_x_at (Human Genome U133 Plus 2.0 Array)   211190_x_at (Human Genome U133 Plus 2.0 Array)   211191_at (Human Genome U133 Plus 2.0 Array)   211192_s_at (Human Genome U133 Plus 2.0 Array)   230391_at (Human Genome U133 Plus 2.0 Array)   244352_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357030
Ensembl peptide - ENSP00000312367
Ensembl peptide - ENSP00000357027
Ensembl peptide - ENSP00000357033
Ensembl peptide - ENSP00000442845
NCBI entrez gene - 8832     See in Manteia.
OMIM - 604513
RefSeq - XM_011510095
RefSeq - NM_001184879
RefSeq - NM_001184881
RefSeq - NM_001184882
RefSeq - NM_003874
RefSeq - XM_011510094
RefSeq Peptide - NP_001171811
RefSeq Peptide - NP_001317671
RefSeq Peptide - NP_003865
RefSeq Peptide - NP_001171808
RefSeq Peptide - NP_001171810
swissprot - Q9UIB8
Ensembl - ENSG00000066294
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Cd84ENSMUSG00000038147Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LY9 / Q9HBG7 / lymphocyte antigen 9ENSG0000012222432
Q9NQ25 / SLAMF7 / SLAM family member 7ENSG0000002675128
Q96DU3 / SLAMF6 / SLAM family member 6ENSG0000016273925
Q96A28 / SLAMF9 / SLAM family member 9ENSG0000016272325


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006952 defense response TAS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules TAS
 biological_processGO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production IDA
 biological_processGO:0032701 negative regulation of interleukin-18 production IDA
 biological_processGO:0033004 negative regulation of mast cell activation IDA
 biological_processGO:0043305 negative regulation of mast cell degranulation IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:2001256 regulation of store-operated calcium entry IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000066294 CD84 / Q9UIB8 / CD84 molecule  / complex / reaction






 

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